S100B impairs glycolysis via enhanced poly(ADP-ribosyl)ation of glyceraldehyde-3-phosphate dehydrogenase in rodent muscle cells.
Am. J. Physiol. Endocrinol. Metab.2017 Jun 01;312(6):E471-E481. Epub 2017 Feb 07
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摘要
myotube cells. We conclude that S100B as a humoral factor may impair glycolysis in muscle cells independent of insulin action, and the effect may be attributed to the inhibition of GAPDH activity from enhanced poly(ADP-ribosyl)ation of the enzyme.
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原始数据
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