| Type | Description |
|---|---|
| Definition | WD repeat domain 76 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:11:00 | WDR76 mediates obesity and hepatic steatosis via HRas destabilization. | 31873167 |
| 2019-02-23 11:30:00 | Study identifies WD40-repeat protein 76 (WDR76) as one of the HRAS binding proteins using proteomic analyses of hepatocellular carcinomas tissue form human patients and mouse diethylnitrosamine-induced liver carcinogenesis model and demonstrates that WDR76 functions as a tumor suppressor via RAS degradation. | 30655611 |
| Type | IDs |
|---|---|
| Synonymous | 5830411K18Rik, 6030457D09, AA517836 |
| Gene |
UniProtKB-ID:
WDR76_MOUSE
UniprotKB:
A6PWY4
UniParc:
UPI000050CD5F,
UPI00017E1325,
UPI00015748BF
EMBL:
AK020004,
BC117822,
AL928678,
BC094676
Ensembl:
ENSMUSG00000027242
KO:
mmu:241627
|
| Nucleutide sequences |
EMBL-CDS:
AAI17823.1,
AAH94676.1,
BAB31961.2
Ensembl_TRS:
ENSMUST00000110603,
ENSMUST00000028676,
ENSMUST00000110602
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106234,
ENSMUSP00000028676,
ENSMUSP00000106232
RefSeq:
XP_011237831.1,
NP_001277916.1,
NP_001277915.1,
NP_001356114.1,
NP_084510.2
|
| Others |
UniRef100:
UniRef100_A6PWY4
UniRef90:
UniRef90_A6PWY4
UniRef50:
UniRef50_A6PWY4
UniGene:
Mm.293284
CCDS:
CCDS89546.1,
CCDS38218.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 32098917 |
Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair. J Biosci Avinash Srivastava , Rakesh K Mishra |
2020-01-01 | - |
| 31873167 |
WDR76 mediates obesity and hepatic steatosis via HRas destabilization. Sci Rep Jong-Chan Park , Woo-Jeong Jeong , Seol Hwa Seo , Kang-Yell Choi |
2019-12-23 | - |
| 30655611 |
WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation. Nat Commun Woo-Jeong Jeong , Jong-Chan Park , Woo-Shin Kim , Eun Ji Ro , Soung Hoo Jeon , Sang-Kyu Lee , Young Nyun Park , Do Sik Min , Kang-Yell Choi |
2019-01-17 | - |
| 26206133 |
Nat Commun Paulina A Latos , Angela Goncalves , David Oxley , Hisham Mohammed , Ernest Turro , Myriam Hemberger |
2015-07-24 | - |
| 22922362 |
Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat. Immunol. Dipayan Rudra , Paul deRoos , Ashutosh Chaudhry , Rachel E Niec , Aaron Arvey , Robert M Samstein , Christina Leslie , Scott A Shaffer , David R Goodlett , Alexander Y Rudensky |
2012-10-01 |
Ldlrap1,
Kifc1,
Noc4l,
Acacb,
Papd4,
Rrp8,
Clk3,
Csnk1d,
Tsr1,
Utp15,
Nckap1l,
Lpxn,
Whsc1,
Chd4,
Bre,
Camk2d,
Foxp1,
Nusap1,
Sp110,
Rap1a,
Sec13,
Rps6ka3,
Cse1l,
Pwp2,
Lims1,
Add1,
Adsl,
Akp3,
Ap1b1,
Ap2a1,
Ap3s1,
Arpc1b,
Atm,
Bax,
Bcl7c,
Bop1,
Runx1,
Cbfb,
Cbx4,
Cct4,
Cd2ap,
Cdk11b,
Cdk6,
Cebpz,
Coro1a,
Coil,
Dbnl,
Dbt,
Dync1h1,
Dnm2,
Ddx19a,
Elf1,
Mark2,
Ercc3,
Igf2bp3,
Fasn,
Fen1,
Gata3,
Nr3c1,
Gspt1,
H1f0,
Hdac2,
Hdac3,
H2afx,
Hk2,
Hnrnpl,
Inpp5d,
Kif11,
Kif4,
Kpna3,
Lat,
Arhgef1,
Lig3,
Nup155,
Pfkfb3,
Max,
Mllt10,
Msh6,
Map4,
Myef2,
Nfatc2,
Ints6,
Zfp638,
Npm3,
Orc1,
Orc2,
Pcx,
Pdcd4,
Pdcd6ip,
Pfkl,
Plec,
Plk1,
Lcp1,
Pold1,
Nup88,
Prpf4b,
Psme3,
Slu7,
Qk
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员