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24158 Acadm

24158

Acadm

acyl-CoA dehydrogenase medium chain

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition acyl-CoA dehydrogenase medium chain

研究结论

Date Results Publications
2011-04-09 10:39:00 High fat diets increase the expression of fatty acid oxidation enzymes such as UCP3,PDK4, and MCAD concomitant with elevated plasma fatty acid levels and the induction of PGC-1 beta, but independent of changes in AMPK, p38, and signaling. 21084676
2010-01-21 00:00:00 these data suggest that octanoic and decanoic acids impair brain mitochondrial energy homeostasis that could underlie at least in part the neuropathology of MCAD deficiency 19703432
2010-01-21 00:00:00 The mutation of this residue to Lys375 allows molecular oxygen to enter into the catalytic site serving as the electron acceptor for the reduced FAD cofactor. 18061544
2010-01-21 00:00:00 expression of rat mitochondrial medium-chain acyl-CoA dehydrogenase wild-type and Arg256 mutant proteins 15358373
2010-01-21 00:00:00 Our present data show that the medium-chain fatty acids that most accumulate in MCAD deficiency cause oxidative stress in rat brain 19428797

名称对应

Type IDs
Synonymous MCAD
Gene
UniProtKB-ID: ACADM_RAT, G3V796_RAT
UniprotKB: P08503, G3V796
UniParc: UPI00001251E8, UPI000019BB6D
EMBL: CH473952, J02791, AABR07013860
Ensembl: ENSRNOG00000009845
KO: rno:24158
Nucleutide sequences
EMBL-CDS: AAA40670.1, EDL82532.1
Gene_ORFName: rCG_28992
Ensembl_TRS: ENSRNOT00000013238
Protein sequencees
Ensembl_PRO: ENSRNOP00000013238
RefSeq: NP_058682.2
Others
UniRef100: UniRef100_P08503, UniRef100_G3V796
UniRef90: UniRef90_P08503
UniRef50: UniRef50_P08503
UniGene: Rn.6302

全选

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研究热度

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