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237868 Sarm1

237868

Sarm1

sterile alpha and HEAT/Armadillo motif containing 1

protein-coding

Mus musculus

基因描述

Type Description
Definition sterile alpha and HEAT/Armadillo motif containing 1

研究结论

Date Results Publications
2021-03-27 14:43:00 SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration. 32609299
2021-02-20 13:31:00 SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration. 33107823
2021-01-16 15:57:00 Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration. 31740269
2020-12-26 13:13:00 cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons. 32087251
2020-11-28 13:10:00 DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon and Promote SARM1-Dependent Axon Degeneration. 31696428

名称对应

Type IDs
Synonymous A830091I15Rik, C78606, MyD885, Sarm
Gene
UniProtKB-ID: SARM1_MOUSE
UniprotKB: Q6PDS3
UniParc: UPI0000470436, UPI00000EADF8, UPI00001D3F76, UPI000050AAF0
EMBL: AK172964, BC058534, AK044113, BC080850, AL591177, AY444167
Ensembl: ENSMUSG00000050132
KO: mmu:237868
Nucleutide sequences
EMBL-CDS: CAI25546.1, CAI25544.1, BAC31784.1, AAH58534.1, BAD32242.1, CAI25545.1, AAH80850.1, AAR17521.1
Ensembl_TRS: ENSMUST00000061174, ENSMUST00000108287
Protein sequencees
Ensembl_PRO: ENSMUSP00000051059, ENSMUSP00000103922
RefSeq: NP_766383.2, NP_001161993.1
Others
UniRef100: UniRef100_Q6PDS3
UniRef90: UniRef90_Q6PDS3
UniRef50: UniRef50_Q6SZW1
UniGene: Mm.210332
CCDS: CCDS25105.1, CCDS48857.1

全选

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