PITPNB - phosphatidylinositol transfer protein beta-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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23760 PITPNB

基因描述

Type	Description
Definition	phosphatidylinositol transfer protein beta

研究结论

Date	Results	Publications
2010-06-28 12:06:00	Phosphatidylinositol and phosphatidylcholine exchange activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.	20332109
2010-01-21 00:00:00	Role of PITPNB- not required for sphingomyelin trafficking	12023904
2010-01-21 00:00:00	The presence of PITPbeta splice variants adds an extra level of proteome complexity	16780419

名称对应

Type	IDs
Synonymous	PI-TP-beta, PtdInsTP, VIB1B
Gene	UniProtKB-ID: PIPNB_HUMAN UniprotKB: P48739 UniParc: UPI000006EE85, UPI0000043C3A, UPI0000EE59E2 EMBL: BC018704, AL031591, AK302367, D30037, CH471095, BC031427, CR456541 Ensembl: ENSG00000180957 KO: hsa:23760
Nucleutide sequences	EMBL-CDS: EAW59743.1, AAH18704.1, BAA06277.1, AAH31427.1, CAG30427.1, BAH13686.1 Ensembl_TRS: ENST00000634017, ENST00000335272, ENST00000320996
Protein sequencees	Ensembl_PRO: ENSP00000487693, ENSP00000334738, ENSP00000321266 RefSeq: NP_001271207.1, XP_011528354.1, NP_001271206.1, XP_016884196.1, NP_036531.1
Others	UniRef100: UniRef100_P48739 UniRef90: UniRef90_P48739 UniRef50: UniRef50_P48739 UniGene: Hs.705323 CCDS: CCDS13842.1, CCDS63432.1, CCDS63433.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32814053	Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker	2020-08-18	-
31091453	PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. Cell Rep Adnan Shami Shah , Alex G Batrouni , Dongsung Kim , Amith Punyala , Wendy Cao , Chun Han , Michael L Goldberg , Marcus B Smolka , Jeremy M Baskin	2019-05-14	-
31046837	Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes. Acta Neuropathol Commun Jee Hoon Lee , Ji-Hye Han , Hyunmi Kim , Sang Myun Park , Eun-Hye Joe , Ilo Jou	2019-05-02	-
29128334	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-ÎºB Signaling. Cell Syst Ramy H Malty , Hiroyuki Aoki , Ashwani Kumar , Sadhna Phanse , Shahreen Amin , Qingzhou Zhang , Zoran Minic , Florian Goebels , Gabriel Musso , Zhuoran Wu , Hosam Abou-Tok , Michael Meyer , Viktor Deineko , Sandy Kassir , Vishaldeep Sidhu , Matthew Jessulat , Nichollas E Scott , Xuejian Xiong , James Vlasblom , Bhanu Prasad , Leonard J Foster , Tiziana Alberio , Barbara Garavaglia , Haiyuan Yu , Gary D Bader , Ken Nakamura , John Parkinson , Mohan Babu	2017-12-27	-
28986522	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Nat Commun Giulia Antoniali , Fabrizio Serra , Lisa Lirussi , Mikiei Tanaka , Chiara D'Ambrosio , Shiheng Zhang , Slobodanka Radovic , Emiliano Dalla , Yari Ciani , Andrea Scaloni , Mengxia Li , Silvano Piazza , Gianluca Tell	2017-10-06	-
26496610	A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , JÃ¼rgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , JÃ¶rg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann	2015-10-22	Cep85l, Rcc1, Zbtb48, Bsdc1, Kifc1, Ccp110, Ints4, Slc6a8, Cenpi, Nup107, Xpo1, Fbxw11, Tubg1, Csnk1d, Bap1, Ptpn23, Tecpr2, Slain1, Ankrd28, Prkaa1, Espl1, Gbf1, Cdc20, Cenpf, Trip11, Mbd5, Kif22, Dut, Srsf1, Actb, Spred2, Akt2, Mta1, Tgs1, Pip4k2c, Ankfy1, Apc, Ar, Rhoa, Atp2a2, Atp5a1, Atp7a, Cep131, Bach1, Bcl7c, Bmpr1a, Brca1, Bub1, Bub1b, C1qbp, Anxa2, Calu, Cbx1, Cbx4, Cct2, Cct3, Cct4, Cct7, Cct8, Cd2ap, Cdk1, Cdc37, Cdh1, Chek1, Cit, Copa, Crebbp, Cry1, Csk, Smc3, Dctn1, Ddb1, Cdk2ap1, Mapre1, Ect2, Eef1a1, Eif3a, Mark2, Evpl, Ewsr1, Wdr5, Dclre1b, Fbl, Fgfr1, Flot1, Flot2, B4galt1, Gnb1, Gspt1, Hdac6, Herc2, Hsf1, Hsph1, Elavl1, Id2, Cyr61, Cep250, Insr, Eif3e
26344197	Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili	2015-09-17	AKT3, MED6, ABI1, GNPDA1, SRA1, TDRD15, HMGN1P30, PDCD6IP, PDCD6, MED16, ADA, CHAF1A, TOM1, RANBP9, SMC4, ARPC4-TTLL3, RBM14-RBM4, RNF103-CHMP3, CHURC1-FNTB, AP1M2, ISY1-RAB43, UBA2, SAE1, FARSB, DNM1L, ABCF2, COX17, SCAMP2, SCAMP3, DPP3, SNUPN, HUWE1, TSSC4, ATP9A, PQBP1, COL4A3BP, PTGES3L-AARSD1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR3, ACTR2, NUBP2, PPIF, LOC101060521, ARPC2, RAD50, ACTR1B, ACTR1A, ADAM8, LRPPRC, PDIA6, TRAP1, BCAP31, NAMPT, RBM12, G3BP1, ABI2, CEBPZ, TRIM28, AASS, ATP6AP2, WASF2, SLC25A13, CDK2, RBM7, ALYREF, TXNDC9, LOC101929876, PSME3, MPHOSPH10, MPHOSPH6, CDK5, NUTF2, EIF1, DDX39A, PSMD14, CDK7, PLIN3, HNRNPR, MRPS31, CDK8, RABEPK, RIDA, SRRM1, CDK9, STAM2, SF3B4, ZMPSTE24, AKAP8, STUB1, STAG1, UBE4B, PRSS16, SIGMAR1, BET1, CWC27, SAP18
25925205	HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP. Cell Oncol (Dordr) Seemana Bhattacharya , Mrinal K Ghosh	2015-08-01	-
25921289	Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Sci Signal Kristina B Emdal , Anna-Kathrine Pedersen , Dorte B Bekker-Jensen , Kalliopi P Tsafou , Heiko Horn , Sven Lindner , Johannes H Schulte , Angelika Eggert , Lars J Jensen , Chiara Francavilla , Jesper V Olsen	2015-04-28	-
23376485	Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. J Proteomics Marco Prunotto , Annarita Farina , Lydie Lane , AgnÃ¨s Pernin , JÃ¼rg Schifferli , Denis F Hochstrasser , Pierre Lescuyer , Solange Moll	2013-04-26	CDH2, GNPDA1, C1orf68, PDCD6IP, PDCD6, TOM1L1, CDH6, IL18BP, DPP3, SNUPN, ARPC5, CDH11, ARPC4, ARPC3, ARPC1B, ACTR3, ACTR2, TSPAN1, ARPC2, ACTR1B, ACTR1A, CDH13, PDIA6, TRAP1, PDZK1IP1, ATP6AP2, DHRS2, NUTF2, FLOT1, PSMD14, RIDA, GLYAT, ZMPSTE24, STUB1, RTN3, LANCL1, CRISP3, SIRPB1, AKR1A1, TFG, TUBA1B, BPNT1, TUBB4B, BTN2A2, NDRG1, RACK1, ST3GAL6, CPQ, WFDC2, BASP1, IFITM3, CDSN, LYPLA1, FAM3C, ACAA2, VAV3, TOMM40, BAIAP2, ATP5H, CEACAM5, CAP1, VAT1, FBLN5, CIB1, GLRX3, PROCR, ARL6IP5, ARPC1A, OLFM4, CEL, CCT7, CCT4, CCT2, NPC2, DNPH1, PAICS, MYL12A, ATP5L, YKT6, PMVK, GNA13, B3GNT2, CCT8, CETP, CFL1, PTGES3, RBBP9, MASP2, CTSC, GIPC1, AHCYL1, IQGAP2, VAMP5, CFTR, ALDH1L1, FTCD, RUVBL2, PGRMC1, FGL2

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