| Type | Description |
|---|---|
| Definition | phospholipase A2 group XV |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 10:29:00 | Zn(2+) was found to inhibit the esterase activity of LPLA2 in a noncompetitive manner exclusively at a neutral pH (between 6.5 and 8.0). Because lysosomes are reservoirs of Zn(2+) in cells, the pH optimum of LPLA2 might allow it to catalyze acyl transfer unimpeded within the organelle. | 30830753 |
| 2019-02-09 11:46:00 | Expression of the NFATC3-PLA2G15 chimera correlated with aggressive disease biology in murine patient-derived T-ALL xenografts, and poor prognosis in human T-ALL patients. | 29330284 |
| 2017-11-18 13:58:00 | findings show that endosomal lipases participate in lipid antigen presentation by processing lipid antigens and have a role in T cell immunity against mycobacteria | 27662254 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| Type | IDs |
|---|---|
| Synonymous | ACS, GXVPLA2, LLPL, LPLA2, LYPLA3 |
| Gene |
UniProtKB-ID:
PAG15_HUMAN
UniprotKB:
Q8NCC3
UniParc:
UPI00000359EF,
UPI00017A7E19
EMBL:
BC011640,
AK001705,
CH471092,
AK300596,
AL110209,
AL389957,
AB017494,
BC062605,
AK222790,
AC020978,
AK074828,
AY358425
Ensembl:
ENSG00000103066
KO:
hsa:23659
|
| Nucleutide sequences |
EMBL-CDS:
AAQ88791.1,
CAB97531.1,
EAW83217.1,
AAH11640.2,
BAG62293.1,
CAB53675.1,
AAH62605.1,
BAG50965.1,
BAA76877.1,
BAD96510.1,
BAC11233.1
Gene_ORFName:
UNQ341/PRO540
Ensembl_TRS:
ENST00000413021,
ENST00000219345
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394197,
ENSP00000219345
RefSeq:
XP_011521281.1,
NP_036452.1,
NP_001350480.1,
XP_011521282.2
|
| Others |
UniRef100:
UniRef100_Q8NCC3
UniRef90:
UniRef90_Q8NCC3
UniRef50:
UniRef50_Q8NCC3
UniGene:
Hs.632199
CCDS:
CCDS10864.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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