| Type | Description |
|---|---|
| Definition | solute carrier family 4, sodium bicarbonate cotransporter, member 5 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-30 10:35:00 | Study shows that the HCO3 (-) transporter NBCe2 in the choroid plexus of the blood-cerebrospinal fluid barrier is absolutely necessary for normalizing cerebrospinal fluid pH during high levels of CO2 . | 29956324 |
| 2015-12-12 12:01:00 | NBCe2 has an important role to regulate urinary acidification and the transport of K(+) and Ca(2+) in the distal nephron | 26109087 |
| 2015-08-29 10:42:00 | In the absence of Na(+)-HCO3 (-) cotransporter electrogenic 2 in the late distal tubule, acid-loaded mice exhibit disinhibition of ENaC-mediated Na(+) reabsorption, which results in Na(+) retention, K(+) wasting, and hypertension. | 25941340 |
| 2012-07-07 10:25:00 | study has shown that SLC4A5 is involved in the regulation of the acid-base balance as well as in the regulation of blood pressure; concludes that the impairment of the function of SLC4A5 favors development of a hypertensive state | 22082831 |
| 2011-11-26 10:35:00 | targeted disruption of the Slc4a5 gene encoding the electrogenic sodium bicarbonate cotransporter NBCe2 results in significant remodeling of choroid plexus epithelial cells, including abnormal mitochondrial distribution. | 21705333 |
| Type | IDs |
|---|---|
| Synonymous | C330006M16, C330016K18Rik |
| Gene |
UniProtKB-ID:
D3YVG0_MOUSE
UniprotKB:
D3YVG0
UniParc:
UPI0000605316
EMBL:
AC160400,
AC159713
Ensembl:
ENSMUSG00000068323
KO:
mmu:232156
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000039212
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041007
RefSeq:
NP_001159539.1,
XP_006506028.1,
XP_006506026.1,
XP_006506027.1,
XP_006506029.1,
XP_006506030.1
|
| Others |
UniRef100:
UniRef100_E9Q3M5
UniRef90:
UniRef90_E9Q3M5
UniRef50:
UniRef50_Q9BY07
UniGene:
Mm.333189
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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