Alkbh2 - alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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231642 Alkbh2

基因描述

Type	Description
Definition	alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase

研究结论

Date	Results	Publications
2017-04-08 10:24:00	These results revealed that N3-ethylthymidine , but not other DNA lesions, could be repaired by Alkbh2 and Alkbh3 in mammalian cells.	26930515
2012-09-15 11:01:00	ALKBH2 and ALKBH3 provide cancer protection similar to that of the DNA glycosylase AAG and display apparent epistasis with Aag	22684101
2012-09-01 11:22:00	Although both Alkbh2 and Alkbh3 can protect against methyl methanesulfonate-induced cell death, only Alkbh2 shows statistically significant protection against mutations following treatment with this exogenous methylating agent.	22429847

名称对应

Type	IDs
Synonymous	9530023G02, AU016977, Abh2, mABH2
Gene	UniProtKB-ID: ALKB2_MOUSE UniprotKB: Q6P6J4 UniParc: UPI0000194BBD EMBL: AK079195, BC062188 Ensembl: ENSMUSG00000044339 KO: mmu:231642
Nucleutide sequences	EMBL-CDS: AAH62188.1, BAC37576.1 Ensembl_TRS: ENSMUST00000112279, ENSMUST00000053657
Protein sequencees	Ensembl_PRO: ENSMUSP00000107898, ENSMUSP00000056043 RefSeq: NP_001346869.1, NP_778181.2, XP_006530353.1, NP_001346870.1, XP_006530355.1
Others	UniRef100: UniRef100_Q6P6J4 UniRef90: UniRef90_Q6P6J4 UniRef50: UniRef50_Q6NS38 UniGene: Mm.332593 CCDS: CCDS19559.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
28726787	ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage. Cell Death Dis Jennifer J Jordan , Sophea Chhim , Carrie M Margulies , Mariacarmela Allocca , Roderick T Bronson , Arne Klungland , Leona D Samson , Dragony Fu	2017-07-20	-
26930515	Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions. ACS Chem. Biol. Changjun You , Pengcheng Wang , Stephanie L Nay , Jianshuang Wang , Xiaoxia Dai , Timothy R O'Connor , Yinsheng Wang	2016-05-20	-
22684101	DNA repair is indispensable for survival after acute inflammation. J. Clin. Invest. Jennifer A Calvo , Lisiane B Meira , Chun-Yue I Lee , Catherine A Moroski-Erkul , Nona Abolhassani , Koli Taghizadeh , Lindsey W Eichinger , Sureshkumar Muthupalani , Line M Nordstrand , Arne Klungland , Leona D Samson	2012-07-01	Alkbh2, Mpg, Alkbh3
22429847	Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts. DNA Repair (Amst.) Stephanie L Nay , Dong-Hyun Lee , Steven E Bates , Timothy R O'Connor	2012-05-01	Alkbh2
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
18519673	AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA. Cancer Res. Jeanette Ringvoll , Marivi N Moen , Line M Nordstrand , Lisiane B Meira , Bo Pang , Anders Bekkelund , Peter C Dedon , Svein Bjelland , Leona D Samson , PÃ¥l Ã Falnes , Arne Klungland	2008-06-01	Alkbh2, Mpg, Alkbh3, alkB, ALKBH2
17967808	EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst	2007-09-01	Gm11696, Gm10589, Apela, Gm10822, Gm2085, Gm2312, Lncenc1, Gm2381, Gm2659, Gm2679, Dynlt1c, Gm3134, Gm3143, Gm3236, Gm3574, Gm3581, Gm3718, Gm3859, Gm3905, Gm3952, Gm3957, Gm3973, Gm12057, Rex2, Gm4218, Gm4225, Gm16476, Gm4407, Gm14410, Gm4420, Gm14005, 1300002E11Rik, Gm4532, Srcap, Gm17789, Gm10751, Gm14321, 0610009E02Rik, Gm12758, Gm11532, Phactr4, Rusc2, AK010878, Gm10778, 5830417I10Rik, Mir1902, Gm15270, Gm11767, Ino80dos, Bsdc1, Gm7645, Gm20590, Slc44a1, Gm15545, Gm17292, 2900009J06Rik, Kifc1, Gm13150, Gm19426, Gm19428, Gm19474, Gm14963, Gm19565, Gm19592, Gm12588, Snhg4, Gm19702, Gm19705, Platr22, Nuggc, Zfp534, Gm19860, Gm11725, Gm19876, Gm19889, Gm16201, Gm13056, Tnfsf13os, Gm19925, Gm19976, Gm20014, Gm16740, Gm20039, Gm20045, AU020206, Ccdc170, Trp53cor1, Gm20266, Gm20324, Zfp518b, Gm14401, AI480526, Pds5b, Ube3c, Gm21297, Akap9, Gm29724, Itfg2, Parp11
16642038	Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA. EMBO J. Jeanette Ringvoll , Line M Nordstrand , Cathrine B VÃ¥gbÃ¸ , Vivi Talstad , Karen Reite , Per Arne Aas , Knut H Lauritzen , Nina Beate Liabakk , Alexandra BjÃ¸rk , Richard William Doughty , PÃ¥l Ã Falnes , Hans E Krokan , Arne Klungland	2006-05-17	Alkbh2, Alkbh3
16174769	Repair of methylation damage in DNA and RNA by mammalian AlkB homologues. J Biol Chem Dong-Hyun Lee , Seung-Gi Jin , Sheng Cai , Yuan Chen , Gerd P Pfeifer , Timothy R O'Connor	2005-11-25	-

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