| Type | Description |
|---|---|
| Definition | glucokinase regulatory protein |
| Date | Results | Publications |
|---|---|---|
| 2018-02-03 11:07:00 | This study showed that Sirt2-dependent GKRP deacetylation improves impaired HGU and suggest that it may be a therapeutic target for type 2 diabetes. | 29296001 |
| 2016-10-01 10:13:00 | Given that acetylated GKRP may affiliate with type-2 diabetes mellitus (T2DM), understanding the mechanism of GKRP acetylation in the liver could reveal novel targets within the GK-GKRP pathway, for treating T2DM and other metabolic pathologies. | 26620281 |
| Type | IDs |
|---|---|
| Synonymous | GKRP |
| Gene |
UniProtKB-ID:
GCKR_MOUSE,
A0A0J9YUI8_MOUSE
UniprotKB:
Q91X44,
A0A0J9YUI8
UniParc:
UPI000058B880,
UPI00000E5F09
EMBL:
BC012412,
AC114619
Ensembl:
ENSMUSG00000059434
KO:
mmu:231103
|
| Nucleutide sequences |
EMBL-CDS:
AAH12412.1
Ensembl_TRS:
ENSMUST00000072228,
ENSMUST00000201166
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000072084,
ENSMUSP00000144202
RefSeq:
XP_006503946.1,
NP_659158.1,
NP_001361670.1,
XP_006503945.1
|
| Others |
UniRef100:
UniRef100_A0A0J9YUI8,
UniRef100_Q91X44
UniRef90:
UniRef90_A0A3L7HB05,
UniRef90_Q07071
UniRef50:
UniRef50_Q14397
UniGene:
Mm.100043
CCDS:
CCDS19182.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29296001 |
Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein. Nat Commun Hitoshi Watanabe , Yuka Inaba , Kumi Kimura , Michihiro Matsumoto , Shuichi Kaneko , Masato Kasuga , Hiroshi Inoue |
2018-01-02 | - |
| 27146480 |
J Lipid Res Jessica M Ferrell , Shannon Boehme , Feng Li , John Y L Chiang |
2016-07-01 | - |
| 26620281 |
Sci Rep Joo-Man Park , Tae-Hyun Kim , Seong-Ho Jo , Mi-Young Kim , Yong-Ho Ahn |
2015-01-01 |
Gck,
Gckr,
EP300,
SIRT2,
GCK,
GCKR
|
| 24879641 |
Hum Mol Genet Matthew G Rees , Anne Raimondo , Jian Wang , Matthew R Ban , Mindy I Davis , Amy Barrett , Jessica Ranft , David Jagdhuhn , Rica Waterstradt , Simone Baltrusch , Anton Simeonov , Francis S Collins , Robert A Hegele , Anna L Gloyn |
2014-10-15 | - |
| 24333860 |
Biochim. Biophys. Acta Martin Tobias Kaminski , Julia Schultz , Rica Waterstradt , Markus Tiedge , Sigurd Lenzen , Simone Baltrusch |
2014-03-01 |
Gck,
Gckr
|
| 23341629 |
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc. Natl. Acad. Sci. U.S.A. Stephen Lumayag , Caroline E Haldin , Nicola J Corbett , Karl J Wahlin , Colleen Cowan , Sanja Turturro , Peter E Larsen , Beatrix Kovacs , P Dane Witmer , David Valle , Donald J Zack , Daniel A Nicholson , Shunbin Xu |
2013-02-05 |
Mthfsl,
Ildr2,
Copg2os2,
Rell1,
Lrrc8c,
Mirc35hg,
Meig1,
Mbnl2,
Mthfs,
Galnt7,
Lmo1,
Cald1,
Cbr3,
Tmbim6,
Msra,
H2,
Abca1,
Ache,
Chrnb1,
Rasa2,
Adssl1,
Prelp,
Iltifb,
Aox1,
Aqp1,
B2m,
Bcl6,
Serping1,
C1qc,
C4b,
Cacna2d3,
Casp7,
Cd44,
Cd9,
Cfi,
Col4a3,
Cp,
Cr1l,
Crym,
Ctbp2,
Cttn,
Dlg4,
Doc2b,
Edn2,
Emx1,
Enc1,
Ephb3,
Ephx2,
Eri3,
Folr1,
Opn1mw,
Gfap,
Glycam1,
Gna14,
Gnb2,
Pdpn,
Gpm6b,
Ptpn6,
Hdc,
Hsd17b2,
Sdc2,
Mdfic,
Kifc3,
Laptm5,
Gzmm,
Arr3,
Lyz2,
Mab21l1,
Marcks,
Mcl1,
Mcm3,
Mef2c,
Mesp1,
Myo10,
Slc25a15,
Osmr,
Lgals3bp,
Psen2,
Tmsb4x,
Pygm,
Rab3d,
Rps17,
S100a1,
S100a6,
Ccl9,
Exoc4,
Sema3b,
Sez6,
Sh2d1a,
Slc12a4,
Slc16a2,
Slc19a1,
Slc1a1,
Slc6a2,
Dtx4,
Klhl29,
Snx30,
Sdc3,
Mtss1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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{{author.size}} |
目前还没有研究热点人员