| Type | Description |
|---|---|
| Definition | TAR DNA binding protein |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS. | 33398173 |
| 2021-03-27 14:42:00 | Mutant TDP-43 Expression Triggers TDP-43 Pathology and Cell Autonomous Effects on Primary Astrocytes: Implications for Non-cell Autonomous Pathology in ALS. | 32410044 |
| 2021-03-27 14:40:00 | Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in of Signaling Endosomes. | 32187538 |
| 2021-03-20 13:25:00 | Cytoplasmic mislocalization and mitochondrial colocalization of TDP-43 are common features between normal aged and young mice. | 32212857 |
| 2021-02-13 13:26:00 | ALS-linked TDP-43(M337V) knock-in mice exhibit splicing deregulation without neurodegeneration. | 31959210 |
| Type | IDs |
|---|---|
| Synonymous | 1190002A23Rik, C85084, TDP-43, Tdp43 |
| Gene |
UniProtKB-ID:
TADBP_MOUSE,
Q8R0B4_MOUSE,
Q544R5_MOUSE,
Q6VYI4_MOUSE,
Q8BUM1_MOUSE,
Q6VYI5_MOUSE,
Q8BLD4_MOUSE
UniprotKB:
Q921F2,
Q8R0B4,
Q544R5,
Q6VYI4,
Q8BUM1,
Q6VYI5,
Q8BLD4
UniParc:
UPI0000027BFD,
UPI00001BE227,
UPI00000019FE,
UPI00000EAA06,
UPI00001BE228,
UPI00000EB47E
EMBL:
AY319514,
BC027772,
AK045495,
AK032199,
AY319516,
AY319515,
AK146002,
BC025544,
GQ428776,
GQ428775,
AL606969,
AY319513,
AK153803,
AK133207,
BC012873,
BC031126,
BC033475,
BC027105,
AK083312
Ensembl:
ENSMUSG00000041459
KO:
mmu:230908
|
| Nucleutide sequences |
EMBL-CDS:
AAH31126.1,
AAH27772.1,
BAE21557.1,
AAH33475.1,
AAH12873.1,
BAE32189.1,
AAH25544.1,
AAP92688.1,
AAH27105.1,
ACV52542.1,
BAC27753.1,
BAE26823.1,
AAP92691.1,
BAC38861.1,
AAP92690.1,
ACV52543.1,
BAC32395.1,
AAP92689.1
Ensembl_TRS:
ENSMUST00000084125,
ENSMUST00000105699,
ENSMUST00000172073,
ENSMUST00000095719,
ENSMUST00000105700,
ENSMUST00000105702,
ENSMUST00000188134,
ENSMUST00000165113,
ENSMUST00000045180,
ENSMUST00000189048
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000081142,
ENSMUSP00000101324,
ENSMUSP00000130963,
ENSMUSP00000093386,
ENSMUSP00000101325,
ENSMUSP00000101327,
ENSMUSP00000038113,
ENSMUSP00000139476,
ENSMUSP00000140364,
ENSMUSP00000129342
RefSeq:
NP_663531.1,
NP_001008545.1,
NP_001003898.1,
NP_001292354.1,
NP_001003899.1,
NP_001008546.1
|
| Others |
UniRef100:
UniRef100_Q6VYI5,
UniRef100_Q8R0B4,
UniRef100_Q8BLD4,
UniRef100_Q8BUM1,
UniRef100_Q6VYI4,
UniRef100_Q921F2
UniRef90:
UniRef90_Q8R0B4,
UniRef90_Q13148,
UniRef90_Q6VYI4,
UniRef90_I6L9G6
UniRef50:
UniRef50_Q13148,
UniRef50_I6L9G6
UniGene:
Mm.22453,
Mm.378962
CCDS:
CCDS38971.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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