| Type | Description |
|---|---|
| Definition | golgi associated, gamma adaptin ear containing, ARF binding protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:37:00 | GGA2 and RAB13 are important specificity determinants for integrin activity-dependent traffic. | 31076515 |
| 2020-05-02 10:09:00 | Data suggest that overexpression of GGA2 in LUAD tumors results in the accumulation of EGFR protein and increased EGFR signaling, which helps drive tumor progression. | 30578931 |
| 2018-12-22 10:31:00 | Study shows that reduced expression of GGA3 resultes in accumulation of endocytosed EGFR within enlarged endosomes. GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth. Finally, GGA2 was upregulated in 30.8% of human hepatocellular carcinomas and 23.3% of colorectal cancers. | 29358589 |
| 2018-07-14 10:06:00 | PI4KIIIbeta interaction with the VHS domain of GGA2 affected PI4KIIIbeta localization. | 28289207 |
| 2018-06-02 10:25:00 | full length alpha2B-AR associated with GGA2 but not GGA1, its third intracellular loop was found to directly interact with both GGA1 and GGA2. More interestingly, further mapping of interaction domains showed that the GGA1 hinge region and the GGA2 GAE domain bound to multiple subdomains of the loop. | 27901063 |
| Type | IDs |
|---|---|
| Synonymous | VEAR |
| Gene |
UniProtKB-ID:
GGA2_HUMAN
UniprotKB:
Q9UJY4
UniParc:
UPI000013EF46
EMBL:
AF233522,
AF165531,
AF323754,
AB029003,
CH471145,
BC000284,
AC002400,
AF190863
Ensembl:
ENSG00000103365
KO:
hsa:23062
|
| Nucleutide sequences |
EMBL-CDS:
BAA83032.1,
AAH00284.1,
AAC05813.1,
AAF35394.1,
AAF42806.1,
AAK38634.1,
EAW55827.1,
EAW55828.1,
AAF05708.1
Ensembl_TRS:
ENST00000309859
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000311962
RefSeq:
XP_016878564.1,
NP_055859.1,
XP_024305968.1
|
| Others |
UniRef100:
UniRef100_Q9UJY4
UniRef90:
UniRef90_Q9UJY4
UniRef50:
UniRef50_Q9UJY4
UniGene:
Hs.460336
CCDS:
CCDS10611.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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