Type | Description |
---|---|
Definition | general transcription factor IIB |
Date | Results | Publications |
---|---|---|
2015-03-21 10:12:00 | by acutely targeting TFIIB, we were able to inhibit selectively the former set of genes and ameliorate pressure overload hypertrophy. | 25398966 |
2014-08-16 11:13:00 | TFIIB co-localizes and interacts with alpha-tubulin during oocyte meiosis in the mouse and depletion of TFIIB causes arrest of subsequent embryo development. | 24244602 |
2010-01-21 00:00:00 | Study suggest that components of the transcription machinery decreased in accordance with cell differentiation and that TFIIB is specifically and rapidly degraded by the ubiquitin-proteasome pathway. | 19393171 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
TF2B_MOUSE,
Q3ULN2_MOUSE
UniprotKB:
P62915,
Q3ULN2
UniParc:
UPI000002852C
EMBL:
AK145403,
AK151577,
AK146910,
AK133097,
AK146666,
AK146223,
BC016637
Ensembl:
ENSMUSG00000028271
KO:
mmu:229906
|
Nucleutide sequences |
EMBL-CDS:
AAH16637.1,
BAE26416.1,
BAE26991.1,
BAE27344.1,
BAE27522.1,
BAE21509.1,
BAE30517.1
Ensembl_TRS:
ENSMUST00000029938
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029938
RefSeq:
NP_663521.1
|
Others |
UniRef100:
UniRef100_P62915
UniRef90:
UniRef90_P62915
UniRef50:
UniRef50_Q00403
UniGene:
Mm.271756
CCDS:
CCDS17882.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
26426291 |
Comprehensive interactome of Otx2 in the adult mouse neural retina. Genesis Bruno Fant , Alexander Samuel , Stéphane Audebert , Agnès Couzon , Salsabiel El Nagar , Nathalie Billon , Thomas Lamonerie |
2015-11-01 |
Psip1,
Cggbp1,
U2af1,
Crx,
Ddx5,
Eef1a1,
Ewsr1,
Fgf2,
Trip12,
Hnrnpk,
Nfix,
Zfp638,
Otx2,
Pabpc1,
Rbbp4,
Rpl6,
Rps29,
Khdrbs1,
Six6,
Tmpo,
Rpl13a,
U2af2,
Rorb,
Gtf2b,
Zfp553,
Dido1,
Pcbp1,
Esrrb,
Rpl8,
Zfp512,
Rpl3,
Rps26,
Zfp385a,
Zscan26,
Nxf1,
Sarnp,
Rps21,
Ddx17,
Zfp787,
Zfp422,
Rpl38,
Luc7l3,
Kat8,
Rpl4,
2700060E02Rik,
Cdk13,
Casz1,
Basp1,
Sfpq,
Cdc5l,
Lancl2,
Poldip3
|
26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
25972180 |
J. Neurosci. José Cánovas , F Andrés Berndt , Hugo Sepúlveda , Rodrigo Aguilar , Felipe A Veloso , MartÃn Montecino , Carlos Oliva , Juan C Maass , Jimena Sierralta , Manuel Kukuljan |
2015-05-13 | - |
25398966 |
Circ Heart Fail Danish Sayed , Zhi Yang , Minzhen He , Jessica M Pfleger , Maha Abdellatif |
2015-01-01 |
Gtf2b
|
25119045 |
A long noncoding RNA protects the heart from pathological hypertrophy. Nature Pei Han , Wei Li , Chiou-Hong Lin , Jin Yang , Ching Shang , Sylvia T Nuernberg , Kevin Kai Jin , Weihong Xu , Chieh-Yu Lin , Chien-Jung Lin , Yiqin Xiong , Huanchieh Chien , Bin Zhou , Euan Ashley , Daniel Bernstein , Peng-Sheng Chen , Huei-Sheng Vincent Chen , Thomas Quertermous , Ching-Pin Chang |
2014-10-02 | - |
25209997 |
Elife Daniil Alpern , Diana Langer , Benoit Ballester , Stephanie Le Gras , Christophe Romier , Gabrielle Mengus , Irwin Davidson |
2014-09-10 | - |
24244602 |
PLoS ONE Hui Liu , Feng-Xia Yin , Chun-Ling Bai , Qi-Yuan Shen , Zhu-Ying Wei , Xin-Xin Li , Hao Liang , Shorgan Bou , Guang-Peng Li |
2013-01-01 |
Tuba1a,
Gtf2b
|
22922362 |
Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat. Immunol. Dipayan Rudra , Paul deRoos , Ashutosh Chaudhry , Rachel E Niec , Aaron Arvey , Robert M Samstein , Christina Leslie , Scott A Shaffer , David R Goodlett , Alexander Y Rudensky |
2012-10-01 |
Ldlrap1,
Kifc1,
Noc4l,
Acacb,
Papd4,
Rrp8,
Clk3,
Csnk1d,
Tsr1,
Utp15,
Nckap1l,
Lpxn,
Whsc1,
Chd4,
Bre,
Camk2d,
Foxp1,
Nusap1,
Sp110,
Rap1a,
Sec13,
Rps6ka3,
Cse1l,
Pwp2,
Lims1,
Add1,
Adsl,
Akp3,
Ap1b1,
Ap2a1,
Ap3s1,
Arpc1b,
Atm,
Bax,
Bcl7c,
Bop1,
Runx1,
Cbfb,
Cbx4,
Cct4,
Cd2ap,
Cdk11b,
Cdk6,
Cebpz,
Coro1a,
Coil,
Dbnl,
Dbt,
Dync1h1,
Dnm2,
Ddx19a,
Elf1,
Mark2,
Ercc3,
Igf2bp3,
Fasn,
Fen1,
Gata3,
Nr3c1,
Gspt1,
H1f0,
Hdac2,
Hdac3,
H2afx,
Hk2,
Hnrnpl,
Inpp5d,
Kif11,
Kif4,
Kpna3,
Lat,
Arhgef1,
Lig3,
Nup155,
Pfkfb3,
Max,
Mllt10,
Msh6,
Map4,
Myef2,
Nfatc2,
Ints6,
Zfp638,
Npm3,
Orc1,
Orc2,
Pcx,
Pdcd4,
Pdcd6ip,
Pfkl,
Plec,
Plk1,
Lcp1,
Pold1,
Nup88,
Prpf4b,
Psme3,
Slu7,
Qk
|
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