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22780 Ikzf3

22780

Ikzf3

IKAROS family zinc finger 3

protein-coding

Mus musculus

基因描述

Type Description
Definition IKAROS family zinc finger 3

研究结论

Date Results Publications
2015-02-14 11:05:00 These data place Aiolos in the emerging gene regulatory network controlling NK-cell maturation and function. 25319415
2012-10-13 11:21:00 study demonstrated that Aiolos silenced the Il2 locus, promoting TH17 differentiation in vitro and in vivo 22751139
2010-09-20 12:16:00 Aiolos and Ikaros bind to the c-myc promoter in vivo and directly suppress c-myc expression in pre-B cells. 20566697
2010-05-20 12:27:00 Aiolos knockout mice develop the symptoms of human systemic lupus erythematosus (SLE). This finding implicates Aiolos as a possible candidate gene for SLE. 12574333
2010-01-21 00:00:00 Failure to generate high affinity plasma cells in the bone marrow and to sustain serum antibody titers is apparent after both primary and secondary immunization of Aiolos(-)(/)(-) mice with a range of hapten concentrations. 14718515

名称对应

Type IDs
Synonymous 5830411O07Rik, Aiolos, Zfpn1a3, Znfn1a3
Gene
UniProtKB-ID: IKZF3_MOUSE
UniprotKB: O08900
UniParc: UPI00001E6563
EMBL: AL591125, AF001293, CH466556, AL591390
Ensembl: ENSMUSG00000018168
KO: mmu:22780
Nucleutide sequences
EMBL-CDS: AAB58795.1, EDL16146.1
Ensembl_TRS: ENSMUST00000103141
Protein sequencees
Ensembl_PRO: ENSMUSP00000099430
RefSeq: NP_035901.1, XP_006533268.1, XP_006533269.1, XP_006533267.1
Others
UniRef100: UniRef100_O08900
UniRef90: UniRef90_O08900
UniRef50: UniRef50_Q9UKT9
UniGene: Mm.133367, Mm.459157
CCDS: CCDS25352.1

全选

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研究热度

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