Type | Description |
---|---|
Definition | IKAROS family zinc finger 3 |
Date | Results | Publications |
---|---|---|
2015-02-14 11:05:00 | These data place Aiolos in the emerging gene regulatory network controlling NK-cell maturation and function. | 25319415 |
2012-10-13 11:21:00 | study demonstrated that Aiolos silenced the Il2 locus, promoting TH17 differentiation in vitro and in vivo | 22751139 |
2010-09-20 12:16:00 | Aiolos and Ikaros bind to the c-myc promoter in vivo and directly suppress c-myc expression in pre-B cells. | 20566697 |
2010-05-20 12:27:00 | Aiolos knockout mice develop the symptoms of human systemic lupus erythematosus (SLE). This finding implicates Aiolos as a possible candidate gene for SLE. | 12574333 |
2010-01-21 00:00:00 | Failure to generate high affinity plasma cells in the bone marrow and to sustain serum antibody titers is apparent after both primary and secondary immunization of Aiolos(-)(/)(-) mice with a range of hapten concentrations. | 14718515 |
Type | IDs |
---|---|
Synonymous | 5830411O07Rik, Aiolos, Zfpn1a3, Znfn1a3 |
Gene |
UniProtKB-ID:
IKZF3_MOUSE
UniprotKB:
O08900
UniParc:
UPI00001E6563
EMBL:
AL591125,
AF001293,
CH466556,
AL591390
Ensembl:
ENSMUSG00000018168
KO:
mmu:22780
|
Nucleutide sequences |
EMBL-CDS:
AAB58795.1,
EDL16146.1
Ensembl_TRS:
ENSMUST00000103141
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099430
RefSeq:
NP_035901.1,
XP_006533268.1,
XP_006533269.1,
XP_006533267.1
|
Others |
UniRef100:
UniRef100_O08900
UniRef90:
UniRef90_O08900
UniRef50:
UniRef50_Q9UKT9
UniGene:
Mm.133367,
Mm.459157
CCDS:
CCDS25352.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员