| Type | Description |
|---|---|
| Definition | SUMO1/sentrin specific peptidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:56:00 | SENP1-mediated NEMO de-SUMOylation inhibits intermittent hypoxia induced inflammatory response of microglia in vitro. | 31549402 |
| 2020-04-18 11:07:00 | Findings show that increased SUMOylation of CD45 via loss of SENP1 suppresses CD45-mediated dephosphorylation of which promotes MDSC development and function, leading to tumorigenesis | 31186231 |
| 2020-02-08 10:48:00 | Neuronal depolarization deactivates the transcription of the SUMO protease Senp1, an important component regulating synaptic transmission, scaling, and plasticity, through Yy1. Yy1 and Senp1 promote the expression of AMPA receptor subunit GluR1, a pivotal component in learning and memory. | 31629407 |
| 2020-02-01 10:35:00 | results reveal that SENP1-Sirt3 signaling modulates Sirt3 activation and mitochondrial metabolism during metabolic stress. | 31302001 |
| 2018-11-24 11:33:00 | endothelial SENP1-mediated SUMOylation drives graft arteriosclerosis by regulating the synergistic effect of GATA2 and NF-kappaB and consequent endothelial dysfunction. | 28569748 |
| Type | IDs |
|---|---|
| Synonymous | 2310046A20Rik, D15Ertd528e, E330036L07Rik, suPr-2 |
| Gene |
UniProtKB-ID:
SENP1_MOUSE,
M0QWX4_MOUSE
UniprotKB:
P59110,
M0QWX4
UniParc:
UPI0000003F72,
UPI0000F4B7F1
EMBL:
AK028565,
AC113444,
AK088597,
AK035581,
BC023129
Ensembl:
ENSMUSG00000033075
KO:
mmu:223870
|
| Nucleutide sequences |
EMBL-CDS:
AAH23129.1,
BAC40442.1,
BAC26011.1,
BAC29112.1
Ensembl_TRS:
ENSMUST00000044189,
ENSMUST00000180657
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046598,
ENSMUSP00000138056
RefSeq:
XP_006520947.1,
XP_006520945.1,
XP_006520943.1,
XP_036015277.1,
XP_030104386.1,
XP_006520946.1,
NP_001366502.1,
XP_030104385.1,
NP_659100.1
|
| Others |
UniRef100:
UniRef100_M0QWX4,
UniRef100_P59110
UniRef90:
UniRef90_P59110
UniRef50:
UniRef50_Q9P0U3
UniGene:
Mm.384023
CCDS:
CCDS49717.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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