| Type | Description |
|---|---|
| Definition | uridine phosphorylase 1 |
| Date | Results | Publications |
|---|---|---|
| 2012-05-12 10:05:00 | Importance of UPase in the activation of fluoropyrimidines, the effect of uridine in protecting normal tissues, and the role for tumor-specific modulation of the phosphorolytic activity in 5-FU or capecitabine-based chemotherapy. | 21954436 |
| 2010-02-15 11:26:00 | Data show that enhanced cytotoxicity of 5-FU by bFGF through modulating the expression of UPP1 at the transcription level. | 19714313 |
| 2010-01-21 00:00:00 | Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice. | 12077348 |
| 2010-01-21 00:00:00 | UPase is a critical enzyme in the regulation of uridine homeostasis and pyrimidine nucleotide metabolism, and 5-fluorouracil activity | 15772079 |
| 2010-01-21 00:00:00 | Thymidine phosphorylase and UPP1 double knockout mice showed increased thymidine and deoxyuridine in tissues and developed encephalopathy. | 19028666 |
| Type | IDs |
|---|---|
| Synonymous | AI325217, UPase, UdRPase, Up, Upp |
| Gene |
UniProtKB-ID:
UPP1_MOUSE,
Q5SUC8_MOUSE
UniprotKB:
P52624,
Q5SUC8
UniParc:
UPI00000218F9
EMBL:
BC036559,
AK136474,
D44464
Ensembl:
ENSMUSG00000020407
KO:
mmu:22271
|
| Nucleutide sequences |
EMBL-CDS:
BAA07916.1,
AAH36559.1,
BAE22993.1
Ensembl_TRS:
ENSMUST00000020677,
ENSMUST00000164791,
ENSMUST00000101525
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099063,
ENSMUSP00000127473,
ENSMUSP00000020677
RefSeq:
NP_001152874.1,
NP_033503.2,
NP_001152873.1,
XP_006514730.1
|
| Others |
UniRef100:
UniRef100_P52624
UniRef90:
UniRef90_P52624
UniRef50:
UniRef50_P52624
UniGene:
Mm.4610
CCDS:
CCDS24432.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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