Ufd1 - ubiquitin recognition factor in ER-associated degradation 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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22230 Ufd1

基因描述

Type	Description
Definition	ubiquitin recognition factor in ER-associated degradation 1

研究结论

Date	Results	Publications
2015-11-07 10:39:00	The study revealed a regulatory role of the p97-Npl4-Ufd1 complex in regulating a partial degradation of the NF-kappaB subunit p100.	26112410
2010-01-21 00:00:00	the p97-Ufd1-Npl4 complex couples ubiquitinated IP(3) receptors to proteasomal degradation and, thus, plays a key role in IP(3) receptor processing	16103111
2010-01-21 00:00:00	structural analysis of the p97-Npl4-Ufd1 interface	17491009

名称对应

Type	IDs
Synonymous	Ufd1l
Gene	UniProtKB-ID: UFD1_MOUSE UniprotKB: P70362 UniParc: UPI00000E6B94 EMBL: CH466521, AK147138, BC006630, U64445, AK169062 Ensembl: ENSMUSG00000005262 KO: mmu:22230
Nucleutide sequences	EMBL-CDS: AAH06630.1, BAE27708.1, BAE40849.1, EDK97535.1, AAD08719.1 Ensembl_TRS: ENSMUST00000005394, ENSMUST00000115578
Protein sequencees	Ensembl_PRO: ENSMUSP00000111241, ENSMUSP00000005394 RefSeq: XP_006522069.1, NP_035802.3, XP_006522070.1, XP_006522068.1
Others	UniRef100: UniRef100_P70362 UniRef90: UniRef90_Q9ES53 UniRef50: UniRef50_Q92890 UniGene: Mm.237594 CCDS: CCDS28028.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
27184122	Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium. Mol. Psychiatry P Devaraju , J Yu , D Eddins , M M Mellado-Lagarde , L R Earls , J J Westmoreland , G Quarato , D R Green , S S Zakharenko	2017-09-01	-
28190767	An Interaction Landscape of Ubiquitin Signaling. Mol. Cell Xiaofei Zhang , Arne H Smits , Gabrielle B A van Tilburg , Pascal W T C Jansen , Matthew M Makowski , Huib Ovaa , Michiel Vermeulen	2017-03-02	-
25452572	Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation. Cereb. Cortex Elizabeth M Paronett , Daniel W Meechan , Beverly A Karpinski , Anthony-Samuel LaMantia , Thomas M Maynard	2015-10-01	-
26112410	The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-ÎºB Signaling via Partial Degradation of the NF-ÎºB Subunit p100. J Biol Chem Zhao Zhang , Yanyan Wang , Chuanchuan Li , Zhubing Shi , Qian Hao , Wenjia Wang , Xiaomin Song , Yun Zhao , Shi Jiao , Zhaocai Zhou	2015-08-07	-
24357327	Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome. Dis Model Mech Beverly A Karpinski , Thomas M Maynard , Matthew S Fralish , Samer Nuwayhid , Irene E Zohn , Sally A Moody , Anthony-S LaMantia	2014-02-01	-
23077214	22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development. Hum. Mol. Genet. Thomas M Maynard , Deepak Gopalakrishna , Daniel W Meechan , Elizabeth M Paronett , Jason M Newbern , Anthony-Samuel LaMantia	2013-01-15	-
22922362	Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat. Immunol. Dipayan Rudra , Paul deRoos , Ashutosh Chaudhry , Rachel E Niec , Aaron Arvey , Robert M Samstein , Christina Leslie , Scott A Shaffer , David R Goodlett , Alexander Y Rudensky	2012-10-01	Ldlrap1, Kifc1, Noc4l, Acacb, Papd4, Rrp8, Clk3, Csnk1d, Tsr1, Utp15, Nckap1l, Lpxn, Whsc1, Chd4, Bre, Camk2d, Foxp1, Nusap1, Sp110, Rap1a, Sec13, Rps6ka3, Cse1l, Pwp2, Lims1, Add1, Adsl, Akp3, Ap1b1, Ap2a1, Ap3s1, Arpc1b, Atm, Bax, Bcl7c, Bop1, Runx1, Cbfb, Cbx4, Cct4, Cd2ap, Cdk11b, Cdk6, Cebpz, Coro1a, Coil, Dbnl, Dbt, Dync1h1, Dnm2, Ddx19a, Elf1, Mark2, Ercc3, Igf2bp3, Fasn, Fen1, Gata3, Nr3c1, Gspt1, H1f0, Hdac2, Hdac3, H2afx, Hk2, Hnrnpl, Inpp5d, Kif11, Kif4, Kpna3, Lat, Arhgef1, Lig3, Nup155, Pfkfb3, Max, Mllt10, Msh6, Map4, Myef2, Nfatc2, Ints6, Zfp638, Npm3, Orc1, Orc2, Pcx, Pdcd4, Pdcd6ip, Pfkl, Plec, Plk1, Lcp1, Pold1, Nup88, Prpf4b, Psme3, Slu7, Qk
22773186	The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins. EMBO J. Rosanna Piccirillo , Alfred L Goldberg	2012-08-01	Vcp
22232657	Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy. Proc. Natl. Acad. Sci. U.S.A. Cecilia Bebeacua , Andreas FÃ¶rster , CiarÃ¡n McKeown , Hemmo H Meyer , Xiaodong Zhang , Paul S Freemont	2012-01-24	-

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