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21959 Tnp2

21959

Tnp2

transition protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition transition protein 2

研究结论

Date Results Publications
2018-05-05 10:48:00 juvenile spermatids from Ip6k1(-/-) mice display premature expression of the transition protein TNP2 and the protamine PRM2 due to translational derepression. 28743739
2016-02-06 12:00:00 The association of Tp2 expression via binding to the conserved RNA binding motifs of GRTH protein and the basis for understanding GRTH in the regulation of the genes essential for germ cell elongation and completion of spermatogenesis is revealed. 25910401
2012-03-03 11:15:00 Testis-specific miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25)-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development. 22086916
2010-11-06 11:06:00 Cannabinoid receptor 1 influences chromatin remodeling in mouse spermatids by affecting content of transition protein 2 mRNA. 20810562
2010-01-21 00:00:00 TPs are required for normal chromatin condensation, for reducing the number of DNA breaks, and for preventing the formation of secondary defects in spermatozoa, eventual loss of genomic integrity, and sterility 15083521

名称对应

Type IDs
Synonymous TP2, Tp-2
Gene
UniProtKB-ID: STP2_MOUSE
UniprotKB: P11378
UniParc: UPI00000E7855
EMBL: AK005689, CT010583, J03494, M60254, BC092529, Z47352, CH466521
Ensembl: ENSMUSG00000043050
KO: mmu:21959
Nucleutide sequences
EMBL-CDS: CAA87413.1, AAA40468.1, AAA40469.1, EDK97324.1, BAB24187.1, AAA40467.1, AAH92529.1
Ensembl_TRS: ENSMUST00000051297
Protein sequencees
Ensembl_PRO: ENSMUSP00000053078
RefSeq: NP_038722.3
Others
UniRef100: UniRef100_P11378
UniRef90: UniRef90_P11101
UniRef50: UniRef50_P11101
UniGene: Mm.206798
CCDS: CCDS27953.1

全选

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研究热度

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