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21954 Tnni3

21954

Tnni3

troponin I, cardiac 3

protein-coding

Mus musculus

基因描述

Type Description
Definition troponin I, cardiac 3

研究结论

Date Results Publications
2021-02-27 13:51:00 Cardiac Troponin I R193H Mutation Is Associated with Mitochondrial Damage in Cardiomyocytes. 33465007
2018-06-23 10:45:00 Pim-1 is a novel kinase that phosphorylates cTnI primarily at Ser23/24 and Ser150 in cardiomyocytes, which in turn may modulate myofilament function under a variety of physiological and pathophysiological conditions. 29544221
2017-09-30 11:12:00 Hyperphosphorylation of this serine199 in cTnI C terminus impacts heart function by depressing diastolic function at baseline and limiting systolic reserve under physiological stresses. Paradoxically, it preserves heart function after ischemia/reperfusion injury, potentially by decreasing proteolysis of cTnI. 28899987
2016-11-05 11:35:00 The contributions of cardiac myosin binding protein C and troponin I phosphorylation to beta-adrenergic enhancement of in vivo cardiac function 26635197
2016-02-06 10:30:00 The difference in myosin regulatory light chain phosphorylation between the ventricles of R21C(+/+) in cardiac troponin I mice likely contributes to observed differences in contractile force and the lower tension monitored in the LV of HCM mice 25961037

名称对应

Type IDs
Synonymous Tn1, cTnI
Gene
UniProtKB-ID: TNNI3_MOUSE, Q497F1_MOUSE
UniprotKB: P48787, Q497F1
UniParc: UPI000016388D
EMBL: AK169223, BC100590, Z22784, BC061171, U09181
Ensembl: ENSMUSG00000035458
KO: mmu:21954
Nucleutide sequences
EMBL-CDS: AAH61171.1, CAA80459.1, AAA19657.1, AAI00591.1, BAE40992.1
Ensembl_TRS: ENSMUST00000098859
Protein sequencees
Ensembl_PRO: ENSMUSP00000096458
RefSeq: XP_017177599.1, NP_033432.1
Others
UniRef100: UniRef100_P48787
UniRef90: UniRef90_P48787
UniRef50: UniRef50_P48787
UniGene: Mm.27674
CCDS: CCDS39736.1

全选

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研究热度

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