| Type | Description |
|---|---|
| Definition | fermitin family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:06:00 | Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1. | 31825843 |
| 2020-09-05 13:53:00 | Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy. | 31767831 |
| 2020-08-29 12:49:00 | Effects of Kindlin-2 on proliferation and migration of VSMC and integrinbeta1 andbeta3 activity via FAK-PI3K signaling pathway. | 32603328 |
| 2020-07-25 12:03:00 | Deleting kindlin-2 expression in adipocytes in mice caused a severe lipodystrophy with drastically reduced adipose tissue mass. Kindlin-2 ablation elevated the blood levels of nonesterified fatty acids and triglycerides, resulting in massive fatty livers in the mutant mice fed with high-fat diet establishing a critical role of kindlin-2 in control of adipogenesis and lipid metabolism as well as bone homeostasis. | 31292295 |
| 2020-04-18 10:18:00 | Kindlin-2 loss reduces the percentage of beta-cells and concomitantly increases that of alpha-cells during early pancreatic development. Genetic activation of beta-catenin in beta-cells restores the diabetes-like phenotypes induced by Kindlin-2 loss. | 31980627 |
| Type | IDs |
|---|---|
| Synonymous | AA960555, Kindlin-2, Mig2, Plekhc1 |
| Gene |
UniProtKB-ID:
FERM2_MOUSE,
Q3TLE2_MOUSE
UniprotKB:
Q8CIB5,
Q3TLE2
UniParc:
UPI00000E8C91
EMBL:
BC034168,
BC033436,
AK166552,
AK079588
Ensembl:
ENSMUSG00000037712
KO:
mmu:218952
|
| Nucleutide sequences |
EMBL-CDS:
AAH34168.1,
BAC37692.1,
AAH33436.1,
BAE38850.1
Ensembl_TRS:
ENSMUST00000045905
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044554
RefSeq:
NP_001347454.1,
NP_001347455.1,
NP_666166.2,
XP_036014451.1,
XP_006518889.2,
XP_036014450.1
|
| Others |
UniRef100:
UniRef100_Q8CIB5
UniRef90:
UniRef90_Q96AC1
UniRef50:
UniRef50_Q96AC1
UniGene:
Mm.210018
CCDS:
CCDS26977.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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