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218756 Slc4a7

218756

Slc4a7

solute carrier family 4, sodium bicarbonate cotransporter, member 7

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 4, sodium bicarbonate cotransporter, member 7

研究结论

Date Results Publications
2020-12-12 13:22:00 Increased Alcohol Consumption in Mice Lacking Sodium Bicarbonate Transporter NBCn1. 32620847
2020-11-21 13:20:00 Deletion of the Na/HCO3 Transporter NBCn1 Protects Hippocampal Neurons from NMDA-induced Seizures and Neurotoxicity in Mice. 31690738
2020-06-27 12:47:00 Disruption of Slc4a10 results in loss of Slc4a7 expression specifically in inner ear fibrocytes but not in other tissues. At the ultrastructural level, mitochondria of spiral ligament knockout fibrocytes show severe alterations. 31001720
2019-03-02 10:20:00 NBCn1 regulates intracellular pH in ErbB2-induced breast cancer tissue by providing a pathway for cellular uptake of HCO3(-), which can neutralize metabolic acidic waste products 29907770
2018-02-10 11:43:00 This study showed that extracellular acidification inhibits NBCn1 and NHE1 activity in VSMCs; NBCn1 is equivalently inhibited when pCO2 is raised or the bicarbonate level decreased. Lowering the sodium level inhibits NBCn1 and NHE1 markedly only below the typical physiological and pathophysiological range. 28319329

名称对应

Type IDs
Synonymous E430014N10Rik, NBC3, NBCn1, NBCn1-G, Tg(Thy1-SNCA)12Mjff
Gene
UniProtKB-ID: U3RF68_MOUSE, F8VQC9_MOUSE
UniprotKB: U3RF68, F8VQC9
UniParc: UPI0003B08711, UPI0000473397
EMBL: JQ073566, CT025538, AC129580, KF279521
Ensembl: ENSMUSG00000021733
KO: mmu:218756
Nucleutide sequences
EMBL-CDS: AGX13877.1, AEY79769.1
Ensembl_TRS: ENSMUST00000057015
Protein sequencees
Ensembl_PRO: ENSMUSP00000058313
RefSeq: XP_017171444.1, XP_017171442.1, NP_001347444.1, NP_001347445.1, NP_001347437.1, NP_001347438.1, NP_001347433.1, NP_001347435.1, XP_006518062.1, NP_001028442.2, XP_006518061.1, NP_001347446.1, NP_001347442.1, NP_001347439.1, NP_001347440.1, NP_001347443.1, NP_001347434.1, NP_001347449.1, NP_001347441.1
Others
UniRef100: UniRef100_F8VQC9, UniRef100_U3RF68
UniRef90: UniRef90_Q9Y6M7, UniRef90_Q9R1N3
UniRef50: UniRef50_Q9Y6M7
UniGene: Mm.258893

全选

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