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21761 Morf4l1

21761

Morf4l1

mortality factor 4 like 1

protein-coding

Mus musculus

基因描述

Type Description
Definition mortality factor 4 like 1

研究结论

Date Results Publications
2021-01-02 12:52:00 MRG15 orchestrates rhythmic epigenomic remodelling and controls hepatic lipid metabolism. 32694659
2018-01-27 10:20:00 In round spermatids, MRG15 colocalizes with splicing factors PTBP1 and PTBP2 at H3K36me3 sites between the exons and single intron of transition nuclear protein 2 (Tnp2). Thus, our results reveal that MRG15 is essential for pre-mRNA splicing during spermatogenesis and that epigenetic regulation of pre-mRNA splicing by histone modification could be useful to understand not only spermatogenesis but also, epigenetic disorder 27573846
2014-06-28 11:47:00 HDAC2-dependent deacetylation of MORF4L1 enhances MORF4L1 homodimerization, thus facilitating the functionality of complex formation to repress cell proliferation. 24451372
2011-10-29 10:35:00 DNA damage foci, as indicated by immunostaining for gammaH2AX and 53BP1, are detectable in a sub-population of Mrg15 deficient NSC cultures under normal growing conditions and the majority of p21-positive cells are also positive for 53BP1 foci. 21621175
2010-01-21 00:00:00 MRG15 has an essential role in embryonic development via chromatin remodeling and transcriptional regulation. 15798182

名称对应

Type IDs
Synonymous MORFRG15, MRG15, TEG-189, Tex189, mKIAA4002
Gene
UniProtKB-ID: MO4L1_MOUSE, Q569V4_MOUSE
UniprotKB: P60762, Q569V4
UniParc: UPI00000E5B16, UPI0000000A79
EMBL: AK169065, AK146210, BC085103, BC103783, AK168327, AK016414, BC092293, BC003894, BC083118, AK168608, AK167079, AK079115, AK168585, AF319621, AK168674, AB042241, AF319620, BC017619
Ensembl: ENSMUSG00000062270
KO: mmu:21761
Nucleutide sequences
EMBL-CDS: AAH83118.1, AAH17619.1, AAK07406.1, BAC37546.1, BAB30219.1, AAK07407.1, AAH03894.1, AAH85103.1, AAH92293.1, BAE40852.1, BAE40524.1, BAE40475.1, BAB58904.1, AAI03784.1, BAE39239.1, BAE40266.1, BAE40454.1, BAE26980.1
Ensembl_TRS: ENSMUST00000169860, ENSMUST00000085248
Protein sequencees
Ensembl_PRO: ENSMUSP00000082346, ENSMUSP00000132020
RefSeq: NP_001344709.1, NP_077751.1, NP_001034236.1
Others
UniRef100: UniRef100_P60762, UniRef100_Q569V4
UniRef90: UniRef90_P60762
UniRef50: UniRef50_P60762
UniGene: Mm.426209
CCDS: CCDS23400.1, CCDS52885.1

全选

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研究热度

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