| Type | Description |
|---|---|
| Definition | exostosin like glycosyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2013-06-01 11:48:00 | EXTL2 functions to suppress GAG biosynthesis that is enhanced by a xylose kinase and the EXTL2-dependent mechanism that regulates GAG biosynthesis might be a "quality control system" for proteoglycans | 23395820 |
| 2010-03-01 11:43:00 | Lysosomal glycosaminoglycan levels in mucopolysaccharidosis are reduced by EXTL2 gene silencing. | 19690583 |
| 2010-01-21 00:00:00 | donor binding appears to undergo two distinct steps, beginning with the N-acetyl group expelling water from the donor- enzyme complex into the bulk solvent followed by positioning of the donor into the binding site for interactions with the enzyme | 15831490 |
| Type | IDs |
|---|---|
| Synonymous | EXTR2 |
| Gene |
UniProtKB-ID:
EXTL2_HUMAN,
Q8N8F1_HUMAN,
F5GZK1_HUMAN
UniprotKB:
Q9UBQ6,
Q8N8F1,
F5GZK1
UniParc:
UPI000012A35B,
UPI000264ECBA,
UPI000006E796
EMBL:
CH471097,
AK096914,
AK312895,
AC104506,
AB009284,
AF000416
Ensembl:
ENSG00000162694
KO:
hsa:2135
|
| Nucleutide sequences |
EMBL-CDS:
AAC02898.1,
BAA24081.1,
EAW72948.1,
EAW72946.1,
BAG35742.1,
EAW72947.1,
BAC04893.1
Gene_ORFName:
hCG_32848
Ensembl_TRS:
ENST00000370114,
ENST00000370113,
ENST00000535414
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359132,
ENSP00000359131,
ENSP00000444385
RefSeq:
XP_011539298.1,
XP_005270678.1,
NP_001248369.1,
NP_001248371.1,
NP_001248370.1,
XP_011539296.1,
NP_001430.1,
XP_016856140.1,
XP_011539297.1,
NP_001028197.1
|
| Others |
UniRef100:
UniRef100_Q8N8F1,
UniRef100_Q9UBQ6,
UniRef100_F5GZK1
UniRef90:
UniRef90_A0A2I3HCR0,
UniRef90_Q9UBQ6
UniRef50:
UniRef50_A0A2I3HCR0,
UniRef50_Q9UBQ6
UniGene:
Hs.357637
CCDS:
CCDS775.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32814053 |
Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker |
2020-08-18 | - |
| 31391242 |
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy. J Cell Sci Marcel Nowak , Benjamin Suenkel , Pablo Porras , Rebekka Migotti , Franziska Schmidt , Melanie Kny , Xiaoxi Zhu , Erich E Wanker , Gunnar Dittmar , Jens Fielitz , Thomas Sommer |
2019-09-06 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27342126 |
Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. Cell Rep George Savidis , William M McDougall , Paul Meraner , Jill M Perreira , Jocelyn M Portmann , Gaia Trincucci , Sinu P John , Aaron M Aker , Nicholas Renzette , Douglas R Robbins , Zhiru Guo , Sharone Green , Timothy F Kowalik , Abraham L Brass |
2016-06-28 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 23376485 |
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. J Proteomics Marco Prunotto , Annarita Farina , Lydie Lane , Agnès Pernin , Jürg Schifferli , Denis F Hochstrasser , Pierre Lescuyer , Solange Moll |
2013-04-26 |
CDH2,
GNPDA1,
C1orf68,
PDCD6IP,
PDCD6,
TOM1L1,
CDH6,
IL18BP,
DPP3,
SNUPN,
ARPC5,
CDH11,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
TSPAN1,
ARPC2,
ACTR1B,
ACTR1A,
CDH13,
PDIA6,
TRAP1,
PDZK1IP1,
ATP6AP2,
DHRS2,
NUTF2,
FLOT1,
PSMD14,
RIDA,
GLYAT,
ZMPSTE24,
STUB1,
RTN3,
LANCL1,
CRISP3,
SIRPB1,
AKR1A1,
TFG,
TUBA1B,
BPNT1,
TUBB4B,
BTN2A2,
NDRG1,
RACK1,
ST3GAL6,
CPQ,
WFDC2,
BASP1,
IFITM3,
CDSN,
LYPLA1,
FAM3C,
ACAA2,
VAV3,
TOMM40,
BAIAP2,
ATP5H,
CEACAM5,
CAP1,
VAT1,
FBLN5,
CIB1,
GLRX3,
PROCR,
ARL6IP5,
ARPC1A,
OLFM4,
CEL,
CCT7,
CCT4,
CCT2,
NPC2,
DNPH1,
PAICS,
MYL12A,
ATP5L,
YKT6,
PMVK,
GNA13,
B3GNT2,
CCT8,
CETP,
CFL1,
PTGES3,
RBBP9,
MASP2,
CTSC,
GIPC1,
AHCYL1,
IQGAP2,
VAMP5,
CFTR,
ALDH1L1,
FTCD,
RUVBL2,
PGRMC1,
FGL2
|
| 23395820 |
J Biol Chem Satomi Nadanaka , Shaobo Zhou , Shoji Kagiyama , Naoko Shoji , Kazuyuki Sugahara , Kazushi Sugihara , Masahide Asano , Hiroshi Kitagawa |
2013-03-29 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21833088 |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature International Multiple Sclerosis Genetics Consortium , Wellcome Trust Case Control Consortium 2 , Stephen Sawcer , Garrett Hellenthal , Matti Pirinen , Chris C A Spencer , Nikolaos A Patsopoulos , Loukas Moutsianas , Alexander Dilthey , Zhan Su , Colin Freeman , Sarah E Hunt , Sarah Edkins , Emma Gray , David R Booth , Simon C Potter , An Goris , Gavin Band , Annette Bang Oturai , Amy Strange , Janna Saarela , Céline Bellenguez , Bertrand Fontaine , Matthew Gillman , Bernhard Hemmer , Rhian Gwilliam , Frauke Zipp , Alagurevathi Jayakumar , Roland Martin , Stephen Leslie , Stanley Hawkins , Eleni Giannoulatou , Sandra D'alfonso , Hannah Blackburn , Filippo Martinelli Boneschi , Jennifer Liddle , Hanne F Harbo , Marc L Perez , Anne Spurkland , Matthew J Waller , Marcin P Mycko , Michelle Ricketts , Manuel Comabella , Naomi Hammond , Ingrid Kockum , Owen T McCann , Maria Ban , Pamela Whittaker , Anu Kemppinen , Paul Weston , Clive Hawkins , Sara Widaa , John Zajicek , Serge Dronov , Neil Robertson , Suzannah J Bumpstead , Lisa F Barcellos , Rathi Ravindrarajah , Roby Abraham , Lars Alfredsson , Kristin Ardlie , Cristin Aubin , Amie Baker , Katharine Baker , Sergio E Baranzini , Laura Bergamaschi , Roberto Bergamaschi , Allan Bernstein , Achim Berthele , Mike Boggild , Jonathan P Bradfield , David Brassat , Simon A Broadley , Dorothea Buck , Helmut Butzkueven , Ruggero Capra , William M Carroll , Paola Cavalla , Elisabeth G Celius , Sabine Cepok , Rosetta Chiavacci , Françoise Clerget-Darpoux , Katleen Clysters , Giancarlo Comi , Mark Cossburn , Isabelle Cournu-Rebeix , Mathew B Cox , Wendy Cozen , Bruce A C Cree , Anne H Cross , Daniele Cusi , Mark J Daly , Emma Davis , Paul I W de Bakker , Marc Debouverie , Marie Beatrice D'hooghe , Katherine Dixon , Rita Dobosi , Bénédicte Dubois , David Ellinghaus , Irina Elovaara , Federica Esposito , Claire Fontenille , Simon Foote , Andre Franke , Daniela Galimberti , Angelo Ghezzi , Joseph Glessner , Refujia Gomez , Olivier Gout , Colin Graham , Struan F A Grant , Franca Rosa Guerini , Hakon Hakonarson , Per Hall , Anders Hamsten , Hans-Peter Hartung , Rob N Heard , Simon Heath , Jeremy Hobart , Muna Hoshi , Carmen Infante-Duarte , Gillian Ingram , Wendy Ingram , Talat Islam , Maja Jagodic , Michael Kabesch , Allan G Kermode , Trevor J Kilpatrick , Cecilia Kim , Norman Klopp , Keijo Koivisto , Malin Larsson , Mark Lathrop , Jeannette S Lechner-Scott , Maurizio A Leone , Virpi Leppä , Ulrika Liljedahl , Izaura Lima Bomfim , Robin R Lincoln , Jenny Link , Jianjun Liu , Aslaug R Lorentzen , Sara Lupoli , Fabio Macciardi , Thomas Mack , Mark Marriott , Vittorio Martinelli , Deborah Mason , Jacob L McCauley , Frank Mentch , Inger-Lise Mero , Tania Mihalova , Xavier Montalban , John Mottershead , Kjell-Morten Myhr , Paola Naldi , William Ollier , Alison Page , Aarno Palotie , Jean Pelletier , Laura Piccio , Trevor Pickersgill , Fredrik Piehl , Susan Pobywajlo , Hong L Quach , Patricia P Ramsay , Mauri Reunanen , Richard Reynolds , John D Rioux , Mariaemma Rodegher , Sabine Roesner , Justin P Rubio , Ina-Maria Rückert , Marco Salvetti , Erika Salvi , Adam Santaniello , Catherine A Schaefer , Stefan Schreiber , Christian Schulze , Rodney J Scott , Finn Sellebjerg , Krzysztof W Selmaj , David Sexton , Ling Shen , Brigid Simms-Acuna , Sheila Skidmore , Patrick M A Sleiman , Cathrine Smestad , Per Soelberg Sørensen , Helle Bach Søndergaard , Jim Stankovich , Richard C Strange , Anna-Maija Sulonen , Emilie Sundqvist , Ann-Christine Syvänen , Francesca Taddeo , Bruce Taylor , Jenefer M Blackwell , Pentti Tienari , Elvira Bramon , Ayman Tourbah , Matthew A Brown , Ewa Tronczynska , Juan P Casas , Niall Tubridy , Aiden Corvin , Jane Vickery , Janusz Jankowski , Pablo Villoslada , Hugh S Markus , Kai Wang , Christopher G Mathew , James Wason , Colin N A Palmer , H-Erich Wichmann , Robert Plomin , Ernest Willoughby , Anna Rautanen , Juliane Winkelmann , Michael Wittig , Richard C Trembath , Jacqueline Yaouanq , Ananth C Viswanathan , Haitao Zhang , Nicholas W Wood , Rebecca Zuvich , Panos Deloukas , Cordelia Langford , Audrey Duncanson , Jorge R Oksenberg , Margaret A Pericak-Vance , Jonathan L Haines , Tomas Olsson , Jan Hillert , Adrian J Ivinson , Philip L De Jager , Leena Peltonen , Graeme J Stewart , David A Hafler , Stephen L Hauser , Gil McVean , Peter Donnelly , Alastair Compston |
2011-08-10 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员