| Type | Description |
|---|---|
| Definition | DND microRNA-mediated repression inhibitor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:25:00 | Dnd1 loss caused defects in both spermatogenesis and oogenesis and results in testicular teratoma incidence. | 32339196 |
| 2020-07-04 12:16:00 | Results suggest multiple DND1 functions and link DND1 to initiation of epigenetic modifications in male germ cells. | 31253634 |
| 2019-04-13 10:18:00 | Cultured Dead-end1 (Dnd1) mutant germ cells (CDGCs) were morphologically similar to embryonic stem cells (ESCs) and could be maintained in the naive pluripotent condition. | 30529251 |
| 2017-08-12 10:21:00 | DND1 binds a UU(A/U) trinucleotide motif predominantly in the 3' untranslated regions of mRNA, and destabilizes target mRNAs through direct recruitment of the CCR4-NOT deadenylase complex. | 28297718 |
| 2016-10-22 11:01:00 | DND1 interacts with NANOS2 to load unique RNAs into the CCR4-NOTdeaden complex; this interaction is mediated by the zinc finger domain of NANOS2, which is essential for its association with target RNAs; DND1 is an essential partner for NANOS2 that leads to the degradation of specific RNAs in male germ cell development | 26589352 |
| Type | IDs |
|---|---|
| Synonymous | BC034897, RBMS4, Ter |
| Gene |
UniProtKB-ID:
DND1_MOUSE
UniprotKB:
Q6VY05
UniParc:
UPI0000027BCD,
UPI00001BE7C1
EMBL:
BC034897,
AY321066
Ensembl:
ENSMUSG00000044595
KO:
mmu:213236
|
| Nucleutide sequences |
EMBL-CDS:
AAQ63636.1,
AAH34897.1
Ensembl_TRS:
ENSMUST00000061522
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000054412
RefSeq:
NP_775559.2
|
| Others |
UniRef100:
UniRef100_Q6VY05
UniRef90:
UniRef90_Q6VY05
UniRef50:
UniRef50_Q6VY05
UniGene:
Mm.234464
CCDS:
CCDS29163.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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