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Dnd1-mediated epigenetic control of teratoma formation in mouse.

Biol Open. 2018 Jan 29;7(1)
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摘要


In addition, Ezh2 expression or Ccnd1 deficiency repressed the reprogramming of PGCs into pluripotent stem cells, which mimicked the conversion of embryonic germ cells into teratoma-forming cells. These results revealed an epigenetic molecular linkage between Dnd1 and the suppression of testicular teratoma formation.

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