| Type | Description |
|---|---|
| Definition | shadow of prion protein |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:27:00 | The Prion-like protein Shadoo is involved in mouse embryonic and mammary development and differentiation. | 32317725 |
| 2020-03-14 11:18:00 | These data are indicative of a physiological pathway to access Sho functions in the nucleus under conditions of impaired proteasomal activity. | 31129810 |
| 2016-08-06 11:59:00 | Data suggest that expression of shadoo in neuron or hepatocyte cell lines induces same toxic phenotype of drug hypersensitivity as prion protein/PrP(-central region); this effect is counteracted by co-expression of PrP-wild-type. | 26721882 |
| 2015-09-26 14:13:00 | No significant differences in survival, the incubation period of prion disease or other disease features were observed between Sho mutant and WT mice | 25495671 |
| 2015-08-01 10:53:00 | These observations suggest that Shadoo can affect the prion replication process by (i) acting as a holdase and (ii) interfering with the dominant-negative inhibitor effect of the C1 fragment. | 25855735 |
| Type | IDs |
|---|---|
| Synonymous | C630041J07 |
| Gene |
UniProtKB-ID:
SPRN_MOUSE
UniprotKB:
Q8BWU1
UniParc:
UPI00000EA75C
EMBL:
BC056484,
AK049995,
AJ621426,
BN000519
Ensembl:
ENSMUSG00000045733
KO:
mmu:212518
|
| Nucleutide sequences |
EMBL-CDS:
AAH56484.1,
BAC34022.1,
CAG34289.1,
CAF18554.1
Ensembl_TRS:
ENSMUST00000059241
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000053901
RefSeq:
NP_898970.1
|
| Others |
UniRef100:
UniRef100_Q8BWU1
UniRef90:
UniRef90_Q8BWU1
UniRef50:
UniRef50_Q8BWU1
UniGene:
Mm.246858
CCDS:
CCDS21966.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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