| Type | Description |
|---|---|
| Definition | general transcription factor IIH, polypeptide 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 11:15:00 | Using quantitative imaging of TFIIH in living mouse cells, we found that these molecules reduce the intracellular concentration of TFIIH and its transcriptional activity to levels similar to that observed in individuals with trichothiodystrophy owing to mutated TTD-A | 30068551 |
| 2015-07-04 15:24:00 | extensive molecular analyses unveiled that wild-type TFIIH cooperated in an ATP-dependent manner with PGC1-alpha as well as with the deacetylase SIRT1, thereby contributing to the PGC1-a deacetylation by SIRT1 | 25340339 |
| 2014-03-29 12:21:00 | Mutations in TFIIH causing trichothiodystrophy are responsible for defects in ribosomal RNA production and processing. | 23562818 |
| 2012-06-23 10:47:00 | Data show that that B2 RNA, when present with Pol II in promoter-bound complexes, specifically represses CTD phosphorylation by TFIIH. | 21326911 |
| 2010-01-21 00:00:00 | Molecular analyses performed on the mice brain tissue demonstrate that TFIIH is required for the stabilization of thyroid hormone receptors (TR) to their DNA-responsive elements. | 17952069 |
| Type | IDs |
|---|---|
| Synonymous | 34kDa, 5033417D07Rik, BTF2, BTF2 p34, C730029A10, D5Ertd679e, TFIIH |
| Gene |
UniProtKB-ID:
TF2H3_MOUSE,
Q3UZB8_MOUSE
UniprotKB:
Q8VD76,
Q3UZB8
UniParc:
UPI0000028A40
EMBL:
AK133941,
BC017515
Ensembl:
ENSMUSG00000029387
KO:
mmu:209357
|
| Nucleutide sequences |
EMBL-CDS:
AAH17515.1,
BAE21939.1
Ensembl_TRS:
ENSMUST00000031333
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031333
RefSeq:
NP_852075.1
|
| Others |
UniRef100:
UniRef100_Q8VD76
UniRef90:
UniRef90_Q8VD76
UniRef50:
UniRef50_Q13889
UniGene:
Mm.185467
CCDS:
CCDS19680.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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