| Type | Description |
|---|---|
| Definition | syntaxin binding protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 12:23:00 | Syntaxin-4 directly binds to E-cadherin and activates part of Smad signals, leading to the disruption of epithelial intercellular adhesion and an augmented expression of fibroblast markers. These findings highlight the importance of local membrane translocation of syntaxin-4 for spatial epithelial-mesenchymal transition in the epithelia and provide new mechanistic insights into asymmetric epithelial morphogenesis. | 29767852 |
| 2015-04-18 11:01:00 | Serine 99 phosphorylation of Synip is required for Glut4 translocation and glucose uptake in both adipocytes and podocytes. | 24705589 |
| 2013-09-14 12:12:00 | synip binding did not prevent the pairing of syntaxin-4 with SNAP-23 to form the binary t-SNARE complex | 23665562 |
| 2011-09-03 11:39:00 | By altering the levels of individual components of the VAMP3/Stx4/SNAP23 complex we show here that this SNARE complex regulates efficient macrophage adhesion, spreading and migration on fibronectin. | 21586284 |
| 2010-01-21 00:00:00 | Syntaxin 4-based SNARE complexes are essential for biphasic insulin granule fusion in pancreatic beta-cells. | 16099818 |
| Type | IDs |
|---|---|
| Synonymous | 6030470M02Rik, Synip |
| Gene |
UniProtKB-ID:
STXB4_MOUSE
UniprotKB:
Q9WV89
UniParc:
UPI00001E6385,
UPI00001E6386,
UPI0000021962,
UPI00001E6382,
UPI00000E8FBB
EMBL:
BC032881,
AF152924,
AL646046,
AK138499
Ensembl:
ENSMUSG00000020546
KO:
mmu:20913
|
| Nucleutide sequences |
EMBL-CDS:
BAE23686.1,
AAH32881.1,
AAD43533.1
Ensembl_TRS:
ENSMUST00000020858,
ENSMUST00000107875,
ENSMUST00000107872,
ENSMUST00000143203
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103507,
ENSMUSP00000116191,
ENSMUSP00000103504,
ENSMUSP00000020858
RefSeq:
XP_030101610.1,
NP_035635.1,
XP_006532801.1,
XP_006532799.1,
XP_006532802.1,
XP_006532800.1,
XP_006532803.1
|
| Others |
UniRef100:
UniRef100_Q9WV89
UniRef90:
UniRef90_Q9WV89
UniRef50:
UniRef50_Q9WV89
UniGene:
Mm.207203
CCDS:
CCDS25242.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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