| Type | Description |
|---|---|
| Definition | NLR family pyrin domain containing 11 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:35:00 | Data suggest that NLRP11 plays novel role in myeloid cells and B-lymphocytes (where NLRP11 expression is high); expression of NLRP11 in both tumor and non-tumor cell lines down-regulates NFkappaB and interferon type I signaling responses. | 29301940 |
| 2018-08-04 12:01:00 | Using MAVS as a platform, NLRP11 degrades TRAF6 to attenuate the production of type I IFNs as well as virus-induced apoptosis. Our findings reveal the regulatory role of NLRP11 in antiviral immunity by disrupting MAVS signalosome. | 29097393 |
| 2010-06-30 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 20403135 |
| 2009-03-25 21:36:00 | Observational study of gene-disease association. (HuGE Navigator) | 19074885 |
| Type | IDs |
|---|---|
| Synonymous | CLR19.6, NALP11, NOD17, PAN10, PYPAF6, PYPAF7 |
| Gene |
UniProtKB-ID:
NAL11_HUMAN
UniprotKB:
P59045
UniParc:
UPI000013ED9D,
UPI0000366E94,
UPI0001C2FAD5
EMBL:
AY154466,
AK090621,
AY226382,
BC034730,
AY168968,
AY095145,
CH471135,
AC012310,
AC008749,
AY168967
Ensembl:
ENSG00000179873
KO:
hsa:204801
|
| Nucleutide sequences |
EMBL-CDS:
AAO18162.1,
BAC03490.1,
AAO12532.1,
EAW72415.1,
AAO59428.1,
AAM14632.1,
AAH34730.1,
AAO12533.1
Ensembl_TRS:
ENST00000589093,
ENST00000589824,
ENST00000592953
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000468082,
ENSP00000466285,
ENSP00000468196
RefSeq:
NP_001284672.1,
NP_001372382.1,
NP_001372380.1,
NP_659444.2
|
| Others |
UniRef100:
UniRef100_P59045
UniRef90:
UniRef90_P59045
UniRef50:
UniRef50_P59045
UniGene:
Hs.375039
CCDS:
CCDS74458.1,
CCDS12935.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
| 29301940 |
J Biol Chem Kornelia Ellwanger , Emily Becker , Ioannis Kienes , Anna Sowa , Yvonne Postma , Yamel Cardona Gloria , Alexander N R Weber , Thomas A Kufer |
2018-02-23 | - |
| 29097393 |
NLRP11 disrupts MAVS signalosome to inhibit type I interferon signaling and virus-induced apoptosis. EMBO Rep Yunfei Qin , Zexiong Su , Yaoxing Wu , Chenglei Wu , Shouheng Jin , Weihong Xie , Wei Jiang , Rongbin Zhou , Jun Cui |
2017-12-01 | - |
| 23307926 |
A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet John R B Perry , Tanguy Corre , Tõnu Esko , Daniel I Chasman , Krista Fischer , Nora Franceschini , Chunyan He , Zoltan Kutalik , Massimo Mangino , Lynda M Rose , Albert Vernon Smith , Lisette Stolk , Patrick Sulem , Michael N Weedon , Wei V Zhuang , Alice Arnold , Alan Ashworth , Sven Bergmann , Julie E Buring , Andrea Burri , Constance Chen , Marilyn C Cornelis , David J Couper , Mark O Goodarzi , Vilmundur Gudnason , Tamara Harris , Albert Hofman , Michael Jones , Peter Kraft , Lenore Launer , Joop S E Laven , Guo Li , Barbara McKnight , Corrado Masciullo , Lili Milani , Nicholas Orr , Bruce M Psaty , ReproGen Consortium , Paul M Ridker , Fernando Rivadeneira , Cinzia Sala , Andres Salumets , Minouk Schoemaker , Michela Traglia , Gérard Waeber , Stephen J Chanock , Ellen W Demerath , Melissa Garcia , Susan E Hankinson , Frank B Hu , David J Hunter , Kathryn L Lunetta , Andres Metspalu , Grant W Montgomery , Joanne M Murabito , Anne B Newman , Ken K Ong , Tim D Spector , Kari Stefansson , Anthony J Swerdlow , Unnur Thorsteinsdottir , Rob M Van Dam , André G Uitterlinden , Jenny A Visser , Peter Vollenweider , Daniela Toniolo , Anna Murray |
2013-04-01 | - |
| 23377640 |
Am J Psychiatry GENDEP Investigators , MARS Investigators , STAR*D Investigators |
2013-02-01 | - |
| 22658674 |
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell Alfredo Castello , Bernd Fischer , Katrin Eichelbaum , Rastislav Horos , Benedikt M Beckmann , Claudia Strein , Norman E Davey , David T Humphreys , Thomas Preiss , Lars M Steinmetz , Jeroen Krijgsveld , Matthias W Hentze |
2012-06-08 |
GNPDA1,
SCARNA27,
GABPB1-AS1,
NFYC-AS1,
FKSG29,
PHKA2-AS1,
HDAC6,
PDCD6,
C17orf96,
LOC100287042,
MIR3652,
ARPC4-TTLL3,
ATP5J2-PTCD1,
TGIF2-C20orf24,
FARSB,
ABCC5,
ABCF2,
HUWE1,
ARPC4,
ARPC1B,
ACTR3,
ACTR1A,
LRPPRC,
TRAP1,
BCAP31,
NAMPT,
RBM12,
TOB1,
G3BP1,
SUGP2,
MBNL2,
ABI2,
CEBPZ,
ATP6AP2,
SLC25A15,
RCL1,
RBM7,
RBM6,
RBM5,
ALYREF,
PSME3,
MPHOSPH10,
NUTF2,
USPL1,
DDX39A,
STX6,
HNRNPR,
MRPS31,
RIDA,
SF3B4,
AKAP8,
STUB1,
SIGMAR1,
SMNDC1,
BCAS2,
SF3A1,
CDKN2A,
APBB3,
SMYD5,
ADAR,
EMC8,
NPM3,
HMG20A,
NOD1,
RACK1,
NDC80,
NSA2,
YAP1,
CD2BP2,
TUBGCP3,
RBM14,
EMG1,
ACAA2,
PPIE,
TAB1,
MAD2L2,
PIBF1,
SLC25A17,
NXF1,
CREB3,
LRRC41,
SYNCRIP,
ENOX2,
MYBBP1A,
DDX17,
ADARB2,
CHERP,
HYOU1,
IPO8,
NOP56,
RNASEH2A,
GLRX3,
DCTN2,
LAMTOR5,
PRDX4,
AGPAT1,
RPP30,
SLU7,
MRPL28
|
| 22267201 |
Nat Genet Lisette Stolk , John R B Perry , Daniel I Chasman , Chunyan He , Massimo Mangino , Patrick Sulem , Maja Barbalic , Linda Broer , Enda M Byrne , Florian Ernst , Tõnu Esko , Nora Franceschini , Daniel F Gudbjartsson , Jouke-Jan Hottenga , Peter Kraft , Patrick F McArdle , Eleonora Porcu , So-Youn Shin , Albert V Smith , Sophie van Wingerden , Guangju Zhai , Wei V Zhuang , Eva Albrecht , Behrooz Z Alizadeh , Thor Aspelund , Stefania Bandinelli , Lovorka Barac Lauc , Jacques S Beckmann , Mladen Boban , Eric Boerwinkle , Frank J Broekmans , Andrea Burri , Harry Campbell , Stephen J Chanock , Constance Chen , Marilyn C Cornelis , Tanguy Corre , Andrea D Coviello , Pio d'Adamo , Gail Davies , Ulf de Faire , Eco J C de Geus , Ian J Deary , George V Z Dedoussis , Panagiotis Deloukas , Shah Ebrahim , Gudny Eiriksdottir , Valur Emilsson , Johan G Eriksson , Bart C J M Fauser , Liana Ferreli , Luigi Ferrucci , Krista Fischer , Aaron R Folsom , Melissa E Garcia , Paolo Gasparini , Christian Gieger , Nicole Glazer , Diederick E Grobbee , Per Hall , Toomas Haller , Susan E Hankinson , Merli Hass , Caroline Hayward , Andrew C Heath , Albert Hofman , Erik Ingelsson , A Cecile J W Janssens , Andrew D Johnson , David Karasik , Sharon L R Kardia , Jules Keyzer , Douglas P Kiel , Ivana Kolcic , Zoltán Kutalik , Jari Lahti , Sandra Lai , Triin Laisk , Joop S E Laven , Debbie A Lawlor , Jianjun Liu , Lorna M Lopez , Yvonne V Louwers , Patrik K E Magnusson , Mara Marongiu , Nicholas G Martin , Irena Martinovic Klaric , Corrado Masciullo , Barbara McKnight , Sarah E Medland , David Melzer , Vincent Mooser , Pau Navarro , Anne B Newman , Dale R Nyholt , N Charlotte Onland-Moret , Aarno Palotie , Guillaume Paré , Alex N Parker , Nancy L Pedersen , Petra H M Peeters , Giorgio Pistis , Andrew S Plump , Ozren Polasek , Victor J M Pop , Bruce M Psaty , Katri Räikkönen , Emil Rehnberg , Jerome I Rotter , Igor Rudan , Cinzia Sala , Andres Salumets , Angelo Scuteri , Andrew Singleton , Jennifer A Smith , Harold Snieder , Nicole Soranzo , Simon N Stacey , John M Starr , Maria G Stathopoulou , Kathleen Stirrups , Ronald P Stolk , Unnur Styrkarsdottir , Yan V Sun , Albert Tenesa , Barbara Thorand , Daniela Toniolo , Laufey Tryggvadottir , Kim Tsui , Sheila Ulivi , Rob M van Dam , Yvonne T van der Schouw , Carla H van Gils , Peter van Nierop , Jacqueline M Vink , Peter M Visscher , Marlies Voorhuis , Gérard Waeber , Henri Wallaschofski , H Erich Wichmann , Elisabeth Widen , Colette J M Wijnands-van Gent , Gonneke Willemsen , James F Wilson , Bruce H R Wolffenbuttel , Alan F Wright , Laura M Yerges-Armstrong , Tatijana Zemunik , Lina Zgaga , M Carola Zillikens , Marek Zygmunt , LifeLines Cohort Study , Alice M Arnold , Dorret I Boomsma , Julie E Buring , Laura Crisponi , Ellen W Demerath , Vilmundur Gudnason , Tamara B Harris , Frank B Hu , David J Hunter , Lenore J Launer , Andres Metspalu , Grant W Montgomery , Ben A Oostra , Paul M Ridker , Serena Sanna , David Schlessinger , Tim D Spector , Kari Stefansson , Elizabeth A Streeten , Unnur Thorsteinsdottir , Manuela Uda , André G Uitterlinden , Cornelia M van Duijn , Henry Völzke , Anna Murray , Joanne M Murabito , Jenny A Visser , Kathryn L Lunetta |
2012-01-22 | - |
| 20403135 |
The genetics of NOD-like receptors in Crohn's disease. Tissue Antigens J R Fraser Cummings , R M Cooney , G Clarke , J Beckly , A Geremia , S Pathan , L Hancock , C Guo , L R Cardon , D P Jewell |
2010-07-01 |
NLRP3,
NLRP13,
NLRP8,
NLRP5,
NLRP4,
NLRP6,
NLRP7,
NLRP11,
NLRP1,
NLRP9,
NLRP10,
NLRP14,
NLRP2,
NLRP12
|
| 19010793 |
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum. Mol. Genet. Sergio E Baranzini , Joanne Wang , Rachel A Gibson , Nicholas Galwey , Yvonne Naegelin , Frederik Barkhof , Ernst-Wilhelm Radue , Raija L P Lindberg , Bernard M G Uitdehaag , Michael R Johnson , Aspasia Angelakopoulou , Leslie Hall , Jill C Richardson , Rab K Prinjha , Achim Gass , Jeroen J G Geurts , Jolijn Kragt , Madeleine Sombekke , Hugo Vrenken , Pamela Qualley , Robin R Lincoln , Refujia Gomez , Stacy J Caillier , Michaela F George , Hourieh Mousavi , Rosa Guerrero , Darin T Okuda , Bruce A C Cree , Ari J Green , Emmanuelle Waubant , Douglas S Goodin , Daniel Pelletier , Paul M Matthews , Stephen L Hauser , Ludwig Kappos , Chris H Polman , Jorge R Oksenberg |
2009-02-15 |
LOC101927998,
CHRND,
AXDND1,
CBLN2,
EN1,
NLRP11,
GPC5,
FOXO3,
WDR7,
RAB38,
CPAMD8,
TRIM42,
PDZRN4,
KCNIP1,
NCKAP5,
IGF2R,
JARID2,
C16orf47,
LEKR1,
MET,
MXI1,
PCSK5,
ACP5,
SLC25A36,
RFK,
RELN,
C1GALT1,
BICD1,
RAD21L1,
SGCD,
CSMD1,
SH3GL2,
SVIL,
UGT1A,
ZIC1,
NUBPL,
BUD13,
ASAP2,
LOC90768,
KCNB2
|
| 19074885 |
Cancer Res. Anna Enjuanes , Yolanda Benavente , Francesc Bosch , Idoia MartÃn-Guerrero , Dolors Colomer , Susana Pérez-Alvarez , Oscar Reina , Maria T Ardanaz , Pedro Jares , Africa GarcÃa-Orad , Miguel A Pujana , Emili Montserrat , Silvia de Sanjosé , Elias Campo |
2008-12-15 |
Il1a,
NAT2,
CDK6,
NOD1,
TNFSF13B,
CAPN9,
CCL27,
RCAN3,
POLI,
ESCO1,
TNFRSF13C,
CCR7,
CCR8,
ACKR2,
NLRP13,
NLRP8,
NLRP5,
CPT1B,
PARP1,
NLRP4,
CYP1A1,
CYP1B1,
CYP2B6,
CYP2C19,
CYP2C8,
CYP2C9,
CYP2C18,
CYP2E1,
ESCO2,
CYP4B1,
NQO1,
RCAN1,
E2F2,
EDN1,
EGF,
EGFR,
ENO2,
NLRP11,
EPHX1,
EPHX2,
ERCC2,
AKT1,
ERCC4,
ERCC5,
ERCC6,
EZH2,
FGF4,
NLRP1,
CARD8,
TNFRSF13B,
ORC3,
ALK,
XRCC6,
POLL,
GSTA2,
GSTM3,
GSTP1,
GSTZ1,
HFE,
APAF1,
HSPA6,
BIRC5,
ICAM1,
NLRP14,
IFNG,
IGF2R,
IL1A,
IL1B,
IL1RN,
IL3,
IL4,
IL4R,
IL5RA,
IL6,
IL6ST,
CXCL8,
IL10,
IL12A,
IL12RB1,
IL13,
IL16,
IL18,
ITGA3,
ITGA4,
ITGAE,
ITGB4,
LIG4,
LTA,
MCM4,
MCM5,
MMP8,
MMP9,
MMP14,
MSH2,
MTHFR,
MTRR,
NBN,
ATM,
NOS2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员