| Type | Description |
|---|---|
| Definition | surfactant associated protein C |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:59:00 | An SFTPC BRICHOS mutant links epithelial ER stress and spontaneous lung fibrosis. | 30721158 |
| 2020-06-13 10:26:00 | CRISPR Sftpc gene editing successfully treats lethal monogenic lung disease in utero in a mouse model. | 31180191 |
| 2020-04-25 11:05:00 | Yap and Taz (Wwtr1) have roles in surfactant protein C-expressing (SPC-expressing) alveolar epithelial type II cells during alveolar epithelial regeneration and resolution of lung inflammation in response to bacterial pneumonia-induced lung injury | 30985294 |
| 2020-01-04 10:43:00 | Epithelial Expression of an Interstitial Lung Disease-Associated Mutation in Surfactant Protein-C Modulates Recruitment and Activation of Key Myeloid Cell Populations in Mice. | 30910861 |
| 2019-09-28 11:04:00 | provide proof of principle that mutant SP-C expression in vivo causes spontaneous lung fibrosis, strengthening the role of alveolar type II cell dysfunction as a key upstream driver of idiopathic pulmonary fibrosis | 29920187 |
| Type | IDs |
|---|---|
| Synonymous | Bricd6, SP-C, SP5, SPC, Sftp-2, Sftp2, pro-SpC |
| Gene |
UniProtKB-ID:
Q6P8P8_MOUSE
UniprotKB:
Q6P8P8
UniParc:
UPI0000021DED
EMBL:
BC061137,
AC122268
Ensembl:
ENSMUSG00000022097
KO:
mmu:20389
|
| Nucleutide sequences |
EMBL-CDS:
AAH61137.1
Ensembl_TRS:
ENSMUST00000022692
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022692
RefSeq:
NP_035489.2
|
| Others |
UniRef100:
UniRef100_Q6P8P8
UniRef90:
UniRef90_P11685
UniRef50:
UniRef50_P11686
UniGene:
Mm.24040
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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