| Type | Description |
|---|---|
| Definition | transmembrane protein 192 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-06 10:38:00 | Authors found that transmembrane protein 192 (TMEM192) interacted with TIG1. Authors also found that both TIG1A and TIG1B isoforms interacted and co-localized with TMEM192 in HtTA cervical cancer cells. The expression of TIG1 induced the expression of autophagy-related proteins. | 27989102 |
| 2012-11-17 11:11:00 | TMEM192 deficiency can induce autophagy in tumor cells, and can further activate apoptosis by the mitochondrial pathway through autophagy. | 22736246 |
| 2010-09-20 11:53:00 | TMEM192 was found to be strongly expressed in human kidney, liver, lung and pancreas tissue. The widespread tissue distribution could suggest an important role of TMEM192 for lysosomal function. | 20370317 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TM192_HUMAN
UniprotKB:
Q8IY95
UniParc:
UPI00000742A4,
UPI000020B691
EMBL:
CH471056,
AK095801,
BC036301,
BX538029
Ensembl:
ENSG00000170088
KO:
hsa:201931
|
| Nucleutide sequences |
EMBL-CDS:
EAX04826.1,
BAC04628.1,
AAH36301.1,
CAD97974.1
Ensembl_TRS:
ENST00000506087,
ENST00000306480
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000425335,
ENSP00000305069
RefSeq:
XP_011530019.1,
NP_001093859.1,
XP_011530020.1
|
| Others |
UniRef100:
UniRef100_Q8IY95
UniRef90:
UniRef90_Q8IY95
UniRef50:
UniRef50_Q8IY95
UniGene:
Hs.704511
CCDS:
CCDS43279.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33144569 |
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export. Nat Commun Dick J H van den Boomen , Agata Sienkiewicz , Ilana Berlin , Marlieke L M Jongsma , Daphne M van Elsland , J Paul Luzio , Jacques J C Neefjes , Paul J Lehner |
2020-11-03 | - |
| 31995728 |
Mol Cell Jingyue Jia , Bhawana Bissa , Lukas Brecht , Lee Allers , Seong Won Choi , Yuexi Gu , Mark Zbinden , Mark R Burge , Graham Timmins , Kenneth Hallows , Christian Behrends , Vojo Deretic |
2020-03-05 | - |
| 28675297 |
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling. J Proteome Res Parveen Kumar , Prathyusha Munnangi , Kvs Rammohan Chowdary , Varun J Shah , Swapnil R Shinde , Nanci R Kolli , Rachita R Halehalli , Hampapathalu A Nagarajaram , Subbareddy Maddika |
2017-08-04 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27989102 |
Tazarotene-Induced Gene 1 Enhanced Cervical Cell Autophagy through Transmembrane Protein 192. Mol. Cells Rong-Yaun Shyu , Chun-Hua Wang , Chang-Chieh Wu , Mao-Liang Chen , Ming-Cheng Lee , Lu-Kai Wang , Shun-Yuan Jiang , Fu-Ming Tsai |
2016-12-01 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 23376485 |
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. J Proteomics Marco Prunotto , Annarita Farina , Lydie Lane , Agnès Pernin , Jürg Schifferli , Denis F Hochstrasser , Pierre Lescuyer , Solange Moll |
2013-04-26 |
CDH2,
GNPDA1,
C1orf68,
PDCD6IP,
PDCD6,
TOM1L1,
CDH6,
IL18BP,
DPP3,
SNUPN,
ARPC5,
CDH11,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
TSPAN1,
ARPC2,
ACTR1B,
ACTR1A,
CDH13,
PDIA6,
TRAP1,
PDZK1IP1,
ATP6AP2,
DHRS2,
NUTF2,
FLOT1,
PSMD14,
RIDA,
GLYAT,
ZMPSTE24,
STUB1,
RTN3,
LANCL1,
CRISP3,
SIRPB1,
AKR1A1,
TFG,
TUBA1B,
BPNT1,
TUBB4B,
BTN2A2,
NDRG1,
RACK1,
ST3GAL6,
CPQ,
WFDC2,
BASP1,
IFITM3,
CDSN,
LYPLA1,
FAM3C,
ACAA2,
VAV3,
TOMM40,
BAIAP2,
ATP5H,
CEACAM5,
CAP1,
VAT1,
FBLN5,
CIB1,
GLRX3,
PROCR,
ARL6IP5,
ARPC1A,
OLFM4,
CEL,
CCT7,
CCT4,
CCT2,
NPC2,
DNPH1,
PAICS,
MYL12A,
ATP5L,
YKT6,
PMVK,
GNA13,
B3GNT2,
CCT8,
CETP,
CFL1,
PTGES3,
RBBP9,
MASP2,
CTSC,
GIPC1,
AHCYL1,
IQGAP2,
VAMP5,
CFTR,
ALDH1L1,
FTCD,
RUVBL2,
PGRMC1,
FGL2
|
| 22736246 |
Oncol. Rep. Zhen Liu , Ya Juan Lv , Yi Peng Song , Xiao Hong Li , Yuan Na Du , Cui Hong Wang , Li Kuan Hu |
2012-09-01 | - |
| 22190034 |
Global landscape of HIV-human protein complexes. Nature Stefanie Jäger , Peter Cimermancic , Natali Gulbahce , Jeffrey R Johnson , Kathryn E McGovern , Starlynn C Clarke , Michael Shales , Gaelle Mercenne , Lars Pache , Kathy Li , Hilda Hernandez , Gwendolyn M Jang , Shoshannah L Roth , Eyal Akiva , John Marlett , Melanie Stephens , Iván D'Orso , Jason Fernandes , Marie Fahey , Cathal Mahon , Anthony J O'Donoghue , Aleksandar Todorovic , John H Morris , David A Maltby , Tom Alber , Gerard Cagney , Frederic D Bushman , John A Young , Sumit K Chanda , Wesley I Sundquist , Tanja Kortemme , Ryan D Hernandez , Charles S Craik , Alma Burlingame , Andrej Sali , Alan D Frankel , Nevan J Krogan |
2012-01-19 |
gag,
gag-pol,
vif,
vpr,
tat,
rev,
vpu,
env,
nef,
ACOT8,
CHAF1A,
SCAMP3,
HUWE1,
PREB,
LRPPRC,
PDIA6,
BCAP31,
AKAP9,
G3BP1,
PSME3,
FLOT1,
CDK9,
STUB1,
CDKN2A,
RTN3,
NPM3,
TOMM40,
CLGN,
ATP5H,
EIF3M,
CARM1,
HYOU1,
SSSCA1,
PRDX4,
ARFGEF2,
ARFGEF1,
SPAG5,
IVNS1ABP,
NFAT5,
NUDC,
PTGES3,
AHCYL1,
MTHFD2,
SDCCAG8,
HSPH1,
PGRMC1,
COPS8,
SF3A3,
PDIA5,
OS9,
LMAN2,
CKAP4,
TMED10,
COPS6,
COPS5,
SLC27A4,
RER1,
PSIP1,
STRAP,
CHI3L2,
DDX20,
CHP1,
PHB2,
OSBPL6,
CKMT1B,
CHCHD1,
LSM12,
MITD1,
COMT,
COX4I1,
COX6B1,
VTI1A,
PARP4,
DPY19L3,
SLC30A7,
CTSB,
CTSD,
DARS,
ZNF579,
TOR1AIP2,
DDB1,
DDX6,
TIMM8A,
DHCR24,
DIAPH1,
DYNC1H1,
DYNC1I2,
DOK1,
DSC3,
DSP,
TOR1A,
AHCY,
FLCN,
TMEM192,
EPRS,
ACSL3,
PTK2B,
TYSND1,
FBN2
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
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目前还没有研究热点人员