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2005 ELK4

2005

ELK4

ETS transcription factor ELK4

protein-coding

Homo sapiens

基因描述

Type Description
Definition ETS transcription factor ELK4

研究结论

Date Results Publications
2017-08-26 12:41:00 Data suggest that SIRT7 undergoes Lys-63 polyubiquitination, later removed by USP7 to repress enzymatic activity of SIRT7; USP7 and SIRT7 regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC); SIRT7 targets G6PC promoter through ELK4. (SIRT7 = sirtuin 7; USP7 = ubiquitin specific peptidase 7; G6PC = glucose-6-phosphatase catalytic subunit; ELK4 = transcription factor ELK4) 28655758
2016-08-29 16:56:00 SLC45A3-ELK4 may represent the first description of a recurrent RNA chimaeric transcript specific to prostate cancer that does not have a detectable DNA aberration 19136943
2016-08-06 11:58:00 ELK4 is overexpressed in melanoma and knocking down the ELK4 or CDK2 expression significantly attenuated the malignant phenotype of melanoma cells 26028036
2016-07-30 10:39:00 CTCF has a role in regulating SLC45A3-ELK4 Chimeric RNA 26938874
2012-12-22 11:36:00 Data suggest that chimeric SLC45A3-ELK4 controls prostate cancer cell proliferation, and the chimera level correlates with prostate cancer disease progression. 22719019

名称对应

Type IDs
Synonymous SAP1
Gene
UniProtKB-ID: ELK4_HUMAN, A0A024R985_HUMAN, Q8IXL1_HUMAN, A0A024R997_HUMAN
UniprotKB: P28324, A0A024R985, Q8IXL1, A0A024R997
UniParc: UPI0000074387, UPI000002A8D2, UPI0000129E67
EMBL: BC063676, M85164, M85165, BC040145, CH471067
Ensembl: ENSG00000158711
KO: hsa:2005
Nucleutide sequences
EMBL-CDS: AAA03631.1, EAW91570.1, AAH63676.1, AAA03632.1, EAW91572.1, EAW91574.1, EAW91573.1, AAH40145.1, EAW91571.1
Gene_ORFName: hCG_18883, hCG_18883
Ensembl_TRS: ENST00000616704, ENST00000357992, ENST00000289703
Protein sequencees
Ensembl_PRO: ENSP00000350681, ENSP00000289703, ENSP00000483628
RefSeq: NP_001964.2, NP_068567.1
Others
UniRef100: UniRef100_A0A024R997, UniRef100_P28324
UniRef90: UniRef90_A0A024R997, UniRef90_P28324
UniRef50: UniRef50_P28324, UniRef50_P41971
UniGene: Hs.497520, Hs.602654
CCDS: CCDS1456.1, CCDS1457.1

全选

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