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19271 Ptprj

19271

Ptprj

protein tyrosine phosphatase, receptor type, J

protein-coding

Mus musculus

基因描述

Type Description
Definition protein tyrosine phosphatase, receptor type, J

研究结论

Date Results Publications
2019-10-26 10:21:00 Study shows that protein tyrosine phosphatase receptor type J (PTPRJ) regulates retinal axonal projections by inhibiting eph and abl kinases in mice. 30082414
2019-10-12 11:12:00 Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in FLT3-ITD acute myeloid leukemia. 29880609
2019-07-06 12:07:00 Ptprj-KO mice exhibit improved glucose and insulin tolerance through enhanced insulin signaling. We herein demonstrated that Ptprj-KO mice exhibited lean phenotypes with lower adiposity because of reduced food intake through enhanced leptin signaling. 28912580
2019-03-23 11:45:00 This study establishes Csk and CD148 as critical molecular switches controlling the thrombotic and hemostatic capacity of platelets and reveals cell-intrinsic mechanisms that prevent pathological thrombosis from occurring. 29301754
2018-01-13 11:20:00 This study demonstrated that the protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinase. 27859601

名称对应

Type IDs
Synonymous AI450271, BET, Byp, CD148, DEP-1, PTPbeta2, Ptpb2, RPTPJ, Scc-1, Scc1
Gene
UniProtKB-ID: PTPRJ_MOUSE, A2AWF8_MOUSE, A2AWF9_MOUSE, E9Q4S7_MOUSE
UniprotKB: Q64455, A2AWF8, A2AWF9, E9Q4S7
UniParc: UPI00005AC68A, UPI000019360E, UPI0000D7785B, UPI000181C109
EMBL: AK147556, AY038861, AK147318, AY039232, AL935132, AY038891, AL954341, AY038877, AL954378, D45212, DQ133576
Ensembl: ENSMUSG00000025314
KO: mmu:19271
Nucleutide sequences
EMBL-CDS: ABA07808.1, AAK98640.1, BAE27993.1, BAA08146.1, AAN11409.1, AAK96030.1, BAE27842.1
Ensembl_TRS: ENSMUST00000111493, ENSMUST00000111495, ENSMUST00000168621
Protein sequencees
Ensembl_PRO: ENSMUSP00000107119, ENSMUSP00000107121, ENSMUSP00000129592
RefSeq: XP_006499054.1, NP_033008.4, XP_006499057.1, XP_036015593.1, XP_006499056.1, NP_001129129.1, XP_006499055.1
Others
UniRef100: UniRef100_Q64455, UniRef100_A2AWF9
UniRef90: UniRef90_A2AWF9, UniRef90_Q64455
UniRef50: UniRef50_Q12913
UniGene: Mm.330393
CCDS: CCDS50630.1

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