| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, receptor type, F |
| Date | Results | Publications |
|---|---|---|
| 2019-03-11 14:28:00 | We show that PTP-3, a LAR homolog in Caenorhabditis elegans, participates in Sema2A-regulated axon guidance. PTPdelta, a member of vertebrate LAR class PTPs, is involved in Sema3A-regulated cortical dendritic growth. In Sema3A signaling, PTPdelta activates Fyn and Src kinases by dephosphorylating their C-terminal Tyr residues. | 28637841 |
| 2017-08-05 10:42:00 | loss of LAR activity resulted in reduced activity of CDK1. | 27352860 |
| 2017-06-24 12:23:00 | Study has identified LAR as a regulator of key signaling pathways, including mTOR and JNK, and has significantly expanded the number of proteins regulated downstream of LAR phosphatase activity. | 27074791 |
| 2016-04-09 11:28:00 | Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural by Signaling Through LAR and RPTPsigma and Modulation of the Rho/ROCK Pathway. | 25703008 |
| 2015-08-01 12:04:00 | This study demonstrates the crucial role of LAR in restricting regrowth of injured CNS axons | 25220840 |
| Type | IDs |
|---|---|
| Synonymous | AA591035, LAR, LARS, RPTP-LAR |
| Gene |
UniProtKB-ID:
PTPRF_MOUSE,
Q3V0J9_MOUSE
UniprotKB:
A2A8L5,
Q3V0J9
UniParc:
UPI000019400B,
UPI00005AB938
EMBL:
AF300943,
AL626764,
AK133085,
BC057166,
AL807774
Ensembl:
ENSMUSG00000033295
KO:
mmu:19268
|
| Nucleutide sequences |
EMBL-CDS:
AAG40194.1,
AAH57166.1,
BAE21505.1
Ensembl_TRS:
ENSMUST00000049074
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039368
RefSeq:
XP_036019783.1,
XP_030109223.1,
XP_036019776.1,
XP_030109220.1,
XP_036019786.1,
XP_036019788.1,
XP_036019789.1,
XP_006502927.1,
XP_036019772.1,
XP_036019780.1,
XP_006502929.1,
XP_006502939.1,
NP_035343.2,
XP_006502932.1,
XP_006502928.1,
XP_006502938.1,
XP_036019781.1,
XP_036019778.1,
XP_006502933.1,
XP_036019782.1,
XP_036019774.1,
XP_036019784.1,
XP_036019787.1,
XP_036019773.1,
XP_030109222.1,
XP_036019775.1,
XP_030109221.1,
XP_006502935.1,
XP_036019779.1,
XP_006502930.1,
XP_036019777.1,
XP_006502937.1,
XP_036019785.1,
XP_006502931.1,
XP_006502934.1
|
| Others |
UniRef100:
UniRef100_Q4U1Z0,
UniRef100_A2A8L5
UniRef90:
UniRef90_A2A8L5,
UniRef90_P10586
UniRef50:
UniRef50_Q64604,
UniRef50_P10586
UniGene:
Mm.29855
CCDS:
CCDS18546.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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