| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:40:00 | Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses. | 32194571 |
| 2021-03-06 13:26:00 | PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion. | 32047502 |
| 2020-10-24 13:57:00 | Deletion of PTPN22 improves effector and memory CD8+ T cell responses to tumors. | 31335326 |
| 2020-05-09 11:18:00 | These results show that PTPN22 promotes intestinal inflammation in IL-10-deficient mice, suggesting that therapeutic targeting of PTPN22 might be beneficial in patients with IBD and mutations in IL-10 and IL-10R. | 31194881 |
| 2020-05-02 11:36:00 | Loss of PTPN22 abrogates the beneficial effect of cohousing-mediated fecal microbiota transfer in murine colitis model. | 31501515 |
| Type | IDs |
|---|---|
| Synonymous | 70zpep, PEP, Ptpn8 |
| Gene |
UniProtKB-ID:
PTN22_MOUSE
UniprotKB:
P29352
UniParc:
UPI0000028D90
EMBL:
BC055377,
M90388
Ensembl:
ENSMUSG00000027843
KO:
mmu:19260
|
| Nucleutide sequences |
EMBL-CDS:
AAA39994.1,
AAH55377.1
Ensembl_TRS:
ENSMUST00000029433
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029433
RefSeq:
XP_006501211.1,
XP_011238344.1,
XP_006501213.1,
NP_033005.1,
XP_017174993.1,
XP_036018851.1,
XP_011238343.1,
XP_006501212.1
|
| Others |
UniRef100:
UniRef100_P29352
UniRef90:
UniRef90_P29352
UniRef50:
UniRef50_Q9Y2R2
UniGene:
Mm.395
CCDS:
CCDS38577.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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