| Type | Description |
|---|---|
| Definition | prostaglandin I2 (prostacyclin) synthase |
| Date | Results | Publications |
|---|---|---|
| 2016-09-24 10:21:00 | Prostacyclin synthase and prostaglandin E synthase-1 cooperatively exacerbate inflammatory reactions but have opposing effects on carcinogenesis. | 26611322 |
| 2013-04-06 10:50:00 | Taken together, our in vitro and in vivo findings show that prostacyclin is secreted from neovessels formed as a result of CNS inflammation | 23042236 |
| 2013-01-05 10:17:00 | Cyclooxygenase-2-derived prostacyclin regulates arterial thrombus formation by suppressing tissue factor in a sirtuin-1-dependent-manner. | 22865892 |
| 2010-01-21 00:00:00 | The results provide strong evidence that the protective effects of COX-2 within the liver are mediated through the production of PGE(2) and PGI(2), which exert anti-inflammatory functions. | 17187424 |
| 2010-01-21 00:00:00 | The two major genetic loci Pgis1 and Pgis2 of murine spondylitis are homologous to chromosome regions in human genome, which control ankylosing spondylitis in human patients. | 16081819 |
| Type | IDs |
|---|---|
| Synonymous | Cyp8, Cyp8a1, Pgis |
| Gene |
UniProtKB-ID:
PTGIS_MOUSE
UniprotKB:
O35074
UniParc:
UPI000000410A
EMBL:
AB001607,
AK076585,
BC062151
Ensembl:
ENSMUSG00000017969
KO:
mmu:19223
|
| Nucleutide sequences |
EMBL-CDS:
BAC36403.1,
AAH62151.1,
BAA21717.1
Ensembl_TRS:
ENSMUST00000018113
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018113
RefSeq:
XP_030104487.1,
NP_032994.1
|
| Others |
UniRef100:
UniRef100_O35074
UniRef90:
UniRef90_O35074
UniRef50:
UniRef50_Q16647
UniGene:
Mm.2339
CCDS:
CCDS17097.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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