| Type | Description |
|---|---|
| Definition | prostaglandin E receptor 2 (subtype EP2) |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:52:00 | Small-molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase-associated malignant glioma growth. | 30761522 |
| 2020-02-22 10:06:00 | this study shows that T cell-intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell-driven inflammation in psoriasis | 29935220 |
| 2018-09-01 10:17:00 | Results show in organotypic hippocampal slice cultures that inflammatory response to either Poly(I:C) or lipopolysaccharide (LPS) are mostly driven by TLR3 & TLR4, respectively, in a microglia-dependent fashion; indicate that activation of EP2 mediated diverse anti-inflammatory effects following Poly(I:C) and LPS challenge possibly by inhibiting molecular pathways with critical contributions in neurodegenerative diseases. | 29226424 |
| 2018-08-04 10:43:00 | The protective effect of the EP2 receptor on TGF-beta1 induced podocyte injury via the PI3K / Akt signaling pathway. | 29746568 |
| 2018-05-26 10:12:00 | EP2 contributes to generating mechanical hyperalgesia through positive feedback upregulation of COX-2 expression in muscle after lengthening contractions | 28759126 |
| Type | IDs |
|---|---|
| Synonymous | EP2, Ptgerep2 |
| Gene |
UniProtKB-ID:
PE2R2_MOUSE,
Q543A9_MOUSE
UniprotKB:
Q62053,
Q543A9
UniParc:
UPI000000187C
EMBL:
AK137515,
D50589,
AK054132,
BC005440
Ensembl:
ENSMUSG00000037759
KO:
mmu:19217
|
| Nucleutide sequences |
EMBL-CDS:
AAH05440.1,
BAA09137.1,
BAE23391.1,
BAC35664.1
Ensembl_TRS:
ENSMUST00000046891
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000038483
RefSeq:
NP_032990.1,
XP_006518783.1
|
| Others |
UniRef100:
UniRef100_Q62053
UniRef90:
UniRef90_Q62053
UniRef50:
UniRef50_Q62053
UniGene:
Mm.4630
CCDS:
CCDS26972.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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