EP2 receptor plays pivotal roles in generating mechanical hyperalgesia after lengthening contractions.
Scand J Med Sci Sports. 2018 Mar;28(3):826-833. doi:10.1111/sms.12954. Epub 2017 Aug 11
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摘要
mice. Injecting an EP2 agonist (ONO-AE1-259-01) into the mouse muscle increased expression of COX-2 mRNA. These results suggest that EP2 contributes to generating mechanical hyperalgesia through positive feedback upregulation of COX-2 expression in muscle after LC.
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基因功能
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原始数据
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文献解读
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