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19119 Prm2

19119

Prm2

protamine 2

protein-coding

Mus musculus

基因描述

Type Description
Definition protamine 2

研究结论

Date Results Publications
2020-05-09 10:48:00 Ppp1cc2 dephosphorylated protamine 2 at serine 56. Introduction of a Prm2 S56A mutation to Hspa4l-null mice restored the malformation of sperm heads and the infertility of Hspa4l (-/-) mice. 30914484
2018-05-19 11:13:00 of Prm2 leads not only to impaired histone to protamine exchange and disturbed DNA-hypercondensation, but also to severe membrane defects resulting in sperm immotility. 27833122
2018-05-05 10:48:00 juvenile spermatids from Ip6k1(-/-) mice display premature expression of the transition protein TNP2 and the protamine PRM2 due to translational derepression. 28743739
2014-03-22 12:13:00 In CBF-A knockout mice, expression of protamine 2 (PRM2) was reduced and the Prm2 mRNA was prematurely translated in a subset of elongating spermatids. 24146628
2012-03-03 11:15:00 Testis-specific miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25)-null mice silences transition protein 2 and protamine 2 messages at sites within coding region: implications of its role in germ cell development. 22086916

名称对应

Type IDs
Synonymous AI528784, Prm-2
Gene
UniProtKB-ID: PRM2_MOUSE, Q545M0_MOUSE
UniprotKB: P07978, Q545M0
UniParc: UPI0000003EAA
EMBL: X14004, X07626, AK005729, M27501, BC049612, Z47352, M16456
Ensembl: ENSMUSG00000038015
KO: mmu:19119
Nucleutide sequences
EMBL-CDS: AAA39986.1, CAA30473.1, CAA32170.1, CAA87411.1, AAH49612.1, AAA39981.1, BAB24208.1
Ensembl_TRS: ENSMUST00000189593, ENSMUST00000037996
Protein sequencees
Ensembl_PRO: ENSMUSP00000139898, ENSMUSP00000047925
RefSeq: NP_032959.1
Others
UniRef100: UniRef100_P07978
UniRef90: UniRef90_P07978
UniRef50: UniRef50_P07978
UniGene: Mm.325769
CCDS: CCDS27955.1

全选

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