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19088 Prkar2b

19088

Prkar2b

protein kinase, cAMP dependent regulatory, type II beta

protein-coding

Mus musculus

基因描述

Type Description
Definition protein kinase, cAMP dependent regulatory, type II beta

研究结论

Date Results Publications
2018-05-19 11:24:00 Prkar2b suppression resulted in MI-stage arrest during oocyte development, and these oocytes exhibited abnormal spindle formation and chromosome aggregation. 29518769
2017-07-01 13:01:00 deficiency induces brownlike adipocytes in inguinal white adipose tissue, increases expression of uncoupling protein1 and other thermogenic genes 27967236
2017-06-24 12:23:00 Data (including data from studies using knockout mice) suggest that S100A1 (S-100 calcium-binding protein A1, alpha chain) is involved in protein kinase A- (RIIalpha and RIIbeta)-dependent signaling resulting in nuclear redistribution/influx of HDAC4 (histone deacetylase 4) in skeletal muscle fibers. 28409622
2016-05-07 10:10:00 modulates the duration of leptin receptor signalling and therefore the magnitude of the catabolic response to leptin. 26381935
2016-04-16 11:34:00 Release of pRIIbeta in the presence of cAMP is reduced by calcium, whereas autophosphorylation at the phosphorylation site inhibits holoenzyme reassociation with the catalytic subunit. 26158466

名称对应

Type IDs
Synonymous AI451071, AW061005, PKARIIbeta, Pkarb2, RII(beta)
Gene
UniProtKB-ID: KAP3_MOUSE
UniprotKB: P31324
UniParc: UPI00000EAD64
EMBL: CT010463, AK041013, AK138963, M68861, BC048710
Ensembl: ENSMUSG00000002997
KO: mmu:19088
Nucleutide sequences
EMBL-CDS: AAA40057.1, AAH48710.1, BAE23838.1, BAC30779.1
Ensembl_TRS: ENSMUST00000036497, ENSMUST00000003079
Protein sequencees
Ensembl_PRO: ENSMUSP00000039797, ENSMUSP00000003079
RefSeq: XP_030102474.1, NP_035288.2, NP_001351336.1, NP_001351337.1
Others
UniRef100: UniRef100_P31324
UniRef90: UniRef90_P31323
UniRef50: UniRef50_P31323
UniGene: Mm.25594
CCDS: CCDS25869.1

全选

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研究热度

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