| Type | Description |
|---|---|
| Definition | POU domain, class 4, transcription factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:55:00 | hearts from male Brn-3b KO mutant mice display contractile dysfunction at baseline but also attenuated hypertrophic responses to AngII treatment. Hearts from AngII-treated male Brn-3b KO mice develop further contractile dysfunction linked to extensive fibrosis/remodelling. | 31413277 |
| 2020-04-18 10:48:00 | analyzed the morphology, number, and general architecture of various neuronal types presynaptic to ganglion cells(Brn3a and Brn3b knockout mice), searching for changes secondary to the decrement in the number of their postsynaptic partners | 27391320 |
| 2018-03-10 10:11:00 | Double morphant embryos targeted with morpholino oligonucleotides to both TFs develop significant cardiac defects (looping abnormalities and valve defects) suggesting essential roles for Brn-3a and Brn-3b in developing hearts. | 28594399 |
| 2017-09-16 12:45:00 | Dlx1 and Dlx2 function both downstream of ATOH7 and in parallel, but cooperative, pathways that involve regulation of Brn3b expression to determine retinal ganglion cell fate. | 28356311 |
| 2017-05-06 20:39:00 | he present Pou4f2-GFP knock-in mouse line is a useful tool for further studies on the differentiation and regeneration of retinal ganglion cells | 27532212 |
| Type | IDs |
|---|---|
| Synonymous | Brn-3.2, Brn-3b, Brn3b, Pou4f-rs1, mBrn3-3R |
| Gene |
UniProtKB-ID:
PO4F2_MOUSE
UniprotKB:
Q63934
UniParc:
UPI0000004183,
UPI0009A0A483
EMBL:
S69351,
S68377,
AK087546
Ensembl:
ENSMUSG00000031688
KO:
mmu:18997
|
| Nucleutide sequences |
EMBL-CDS:
BAC39921.1,
AAB30578.1,
AAC60672.1
Ensembl_TRS:
ENSMUST00000034115
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034115
RefSeq:
NP_620394.2
|
| Others |
UniRef100:
UniRef100_Q63934
UniRef90:
UniRef90_Q12837
UniRef50:
UniRef50_Q12837
UniGene:
Mm.234261
CCDS:
CCDS22429.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员