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18795 Plcb1

18795

Plcb1

phospholipase C, beta 1

protein-coding

Mus musculus

基因描述

Type Description
Definition phospholipase C, beta 1

研究结论

Date Results Publications
2020-06-06 11:48:00 The present study showed that PLC-beta1 was crucial for beta-cell function by generation of each PLC-beta conditional knockout mouse. Mice lacking PLC-beta1 in beta cells exhibited a marked defect in glucose-stimulated insulin secretion, leading to glucose intolerance. 31268747
2020-02-01 13:12:00 Phospholipase C-Beta1 reduction leads to disturbances to beta and gamma oscillatory dynamics and pre-pulse inhibition behavior in an animal model of schizophrenia. 30517689
2018-03-10 10:45:00 Data show that phospholipase C (PLC)-beta1 (PLC-beta1) overexpression determines an increase in beta-catenin translocation and that PLC-beta1, inositol polyphosphate multikinase (IPMK) and beta-catenin are mediators of the same signaling pathway. 27563828
2017-12-02 10:11:00 functions in plasma membrane remodeling, particularly caveolae formation 27342861
2017-11-18 11:31:00 Plcb1 plays a crucial role in the initiation of the genetic program responsible for muscle differentiation and osteogenesis. (Review) 27776973

名称对应

Type IDs
Synonymous 3110043I21Rik, AI132408, Plcb, mKIAA0581
Gene
UniProtKB-ID: PLCB1_MOUSE, Q3UPW0_MOUSE
UniprotKB: Q9Z1B3, Q3UPW0
UniParc: UPI00005AC1B3, UPI0000022B45, UPI0000022B48, UPI000217CB59
EMBL: U85713, AL935278, U85712, U85714, AF022801, BC058710, AL928635, AK143153, AF498249, AL928956, X95344, AL840635, AF498250
Ensembl: ENSMUSG00000051177
KO: mmu:18795
Nucleutide sequences
EMBL-CDS: AAD00571.1, AAH58710.1, AAD00573.1, AAD01749.1, CAA64637.1, AAM22966.1, AAD00572.1, AAM22967.1, BAE25284.1
Ensembl_TRS: ENSMUST00000070724, ENSMUST00000110116, ENSMUST00000131552
Protein sequencees
Ensembl_PRO: ENSMUSP00000105743, ENSMUSP00000118756, ENSMUSP00000064844
RefSeq: NP_062651.2, XP_036015453.1, NP_001139302.1, XP_006498993.1
Others
UniRef100: UniRef100_Q9Z1B3, UniRef100_Q3UPW0
UniRef90: UniRef90_Q3UPW0, UniRef90_Q9Z1B3
UniRef50: UniRef50_A4IGD0, UniRef50_Q9Z1B3
UniGene: Mm.330607
CCDS: CCDS16787.1, CCDS50729.1

全选

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