| Type | Description |
|---|---|
| Definition | phosphoinositide-3-kinase regulatory subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:46:00 | Anthrax lethal factor cleaves regulatory subunits of phosphoinositide-3 kinase to contribute to toxin lethality. | 32895527 |
| 2017-09-09 13:06:00 | p85beta deficiency does not alter NK cell differentiation and maturation in spleen or bone marrow. NK cells from p85beta(-/-) mice nonetheless produced more IFN-gamma and degranulated more effectively when stimulated with anti-NKG2D antibody. p85beta deficiency impaired NKG2D internalization, which could contribute to the activated phenotype. | 27381007 |
| 2013-08-31 11:14:00 | Activation of PI3K (p110beta and p85beta), and phospho-AKT (Ser473), participated in the regulation of activating macrophages by wear particles, ultimately resulting in the secretion of TNF-alpha. | 23330804 |
| 2012-11-24 11:00:00 | miR-126-mediated phosphoinositide-3-kinase regulation, not only fine-tunes VEGF-signaling, but it strongly enhances the activities of Ang-1 on vessel stabilization and maturation. | 22867989 |
| 2012-10-06 11:36:00 | p85beta phosphoinositide 3-kinase subunit regulates tumor progression | 22733740 |
| Type | IDs |
|---|---|
| Synonymous | p85beta |
| Gene |
UniProtKB-ID:
P85B_MOUSE
UniprotKB:
O08908
UniParc:
UPI000024DFD5
EMBL:
CH466569,
BC085501,
BC006796,
Y13569
Ensembl:
ENSMUSG00000031834,
ENSMUSG00000111826
KO:
mmu:18709
|
| Nucleutide sequences |
EMBL-CDS:
CAA73903.1,
AAH85501.1,
EDL28873.1,
AAH06796.1
Ensembl_TRS:
ENSMUST00000214106,
ENSMUST00000034296
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034296,
ENSMUSP00000151035
RefSeq:
XP_036009718.1,
NP_032867.2
|
| Others |
UniRef100:
UniRef100_O08908
UniRef90:
UniRef90_O08908
UniRef50:
UniRef50_O00459
UniGene:
Mm.12945
CCDS:
CCDS22381.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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