Type | Description |
---|---|
Definition | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
Date | Results | Publications |
---|---|---|
2020-09-12 16:04:00 | Activated PI3Kdelta breaches multiple B cell tolerance checkpoints and causes autoantibody production. | 31841125 |
2020-07-04 10:40:00 | We conclude that inhibiting PI3Kdelta represents a novel therapeutic approach to ameliorate Alzheimer's disease pathology by dampening plaque accumulation and microglial-dependent neuroinflammation | 31363064 |
2020-06-27 10:18:00 | PI3KCD overactivation caused substantial increases in numbers of memory and follicular helper T (TFH) cells and dramatic changes in cytokine production in both patients and mice. | 30738173 |
2020-06-20 11:23:00 | PI3Kdelta-signaling mediates regulatory B cell immune differentiation when stimulated with resident microbiota or their components, and is critical for induction and regulatory function of IL-10-producing B cells in intestinal homeostasis and inflammation. | 31546615 |
2020-04-11 10:13:00 | 3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one enhanced the therapeutic efficacy of anti-PD1 antibody through inhibiting PI3Kdelta/gamma. | 31691624 |
Type | IDs |
---|---|
Synonymous | 2410099E07Rik, 2610208K16Rik, AW545373, p110delta |
Gene |
UniProtKB-ID:
PK3CD_MOUSE,
Q3T9Y0_MOUSE,
Q8CI98_MOUSE,
Q8BS14_MOUSE,
Q3TBW3_MOUSE,
Q3UDT3_MOUSE
UniprotKB:
O35904,
Q3T9Y0,
Q8CI98,
Q8BS14,
Q3TBW3,
Q3UDT3
UniParc:
UPI00000E8BC2,
UPI00001D686E,
UPI000287A2DC,
UPI00000EAD57,
UPI00005B2759,
UPI0000356973,
UPI000056681C
EMBL:
AK040867,
AL607078,
CU207384,
AF532989,
AL626808,
AK171025,
CH466594,
AK172222,
BC035203,
AK149935,
U86587,
CT010349
Ensembl:
ENSMUSG00000039936
KO:
mmu:18707
|
Nucleutide sequences |
EMBL-CDS:
AAC25676.1,
AAN05615.1,
EDL14872.1,
BAE42890.1,
CAJ18557.1,
AAH35203.2,
BAC30725.1,
BAE42194.1,
BAE29178.1
Ensembl_TRS:
ENSMUST00000105689,
ENSMUST00000105690,
ENSMUST00000177654,
ENSMUST00000038859,
ENSMUST00000118704,
ENSMUST00000105688
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000101314,
ENSMUSP00000101315,
ENSMUSP00000136045,
ENSMUSP00000036434,
ENSMUSP00000112863,
ENSMUSP00000101313
RefSeq:
XP_030109175.1,
XP_006538704.1,
XP_030109174.1,
XP_006538705.1,
NP_001157524.1,
XP_036019723.1,
XP_006538711.1,
XP_017175526.1,
XP_006538712.1,
XP_036019724.1,
XP_006538710.1,
XP_006538707.1,
XP_036019725.1,
XP_006538715.1,
XP_036019722.1,
XP_006538713.1,
XP_006538706.1,
XP_006538714.1,
XP_006538709.1,
NP_001157521.1,
NP_001025008.2,
XP_030109173.1,
XP_017175527.1,
NP_001157523.1,
NP_032866.2,
XP_006538716.1,
NP_001157522.1,
XP_006538708.1
|
Others |
UniRef100:
UniRef100_O35904,
UniRef100_Q3T9Y0,
UniRef100_Q3UDT3,
UniRef100_Q8BS14,
UniRef100_Q8CI98,
UniRef100_Q3TBW3
UniRef90:
UniRef90_Q3TBW3,
UniRef90_H0VMM3,
UniRef90_Q3T9Y0,
UniRef90_O00329
UniRef50:
UniRef50_O00329
UniGene:
Mm.229108
CCDS:
CCDS51380.1
|