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18667 Pgr

18667

Pgr

progesterone receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition progesterone receptor

研究结论

Date Results Publications
2021-03-06 13:26:00 Uterine Epithelial Progesterone Receptor Governs Uterine Receptivity Through Epithelial 33099617
2019-09-28 12:37:00 Paternal developmental TCDD exposure is associated with transgenerational placental dysfunction, suggesting epigenetic modifications within the sperm have occurred. To assess if Pgr and Igf2 DNA methylation changes were present in sperm and persist in future generations, we assessed methylation and expression of these genes in F1/F3 sperm and F3-derived placentae. 29741588
2019-05-11 11:48:00 Endogenous C/EBPbeta and c-Jun stimulated a PR promoter-reporter and these two factors showed promoter occupancy on the endogenous PR gene. 29870755
2019-03-02 10:47:00 Demonstrate that the transcription factor Forkhead Box O1 (FOXO1) is a critical regulator of endometrial receptivity in vivo. Uterine ablation of Foxo1 using the progesterone receptor Cre (PgrCre) model resulted in infertility due to altered epithelial cell polarity and apoptosis, preventing the embryo from penetrating the luminal epithelium. 30452456
2018-06-30 11:49:00 Downregulation of the PGRA isoform at the window of receptivity is necessary to produce a receptive environment for the attaching embryo. 28203817

名称对应

Type IDs
Synonymous 9930019P03Rik, BB114106, NR3C3, PR, PR-A, PR-B
Gene
UniProtKB-ID: PRGR_MOUSE, Q8BW69_MOUSE
UniprotKB: Q00175, Q8BW69
UniParc: UPI00000238E4, UPI00015AA612, UPI00000EA81F
EMBL: BC145807, U12644, AC160964, CH466522, AC113506, AK054117, M68915
Ensembl: ENSMUSG00000031870
KO: mmu:18667
Nucleutide sequences
EMBL-CDS: AAA39971.1, AAA66067.1, AAI45808.1, EDL24960.1, BAC35662.1
Ensembl_TRS: ENSMUST00000189181, ENSMUST00000070463, ENSMUST00000098986
Protein sequencees
Ensembl_PRO: ENSMUSP00000140124, ENSMUSP00000063562, ENSMUSP00000096584
RefSeq: NP_032855.2, XP_006509911.1
Others
UniRef100: UniRef100_Q00175
UniRef90: UniRef90_Q63449
UniRef50: UniRef50_P06401
UniGene: Mm.12798, Mm.437703
CCDS: CCDS22816.1

全选

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