例如:"NBL1", "4681", "drought"
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18541 Pcnt

18541

Pcnt

pericentrin (kendrin)

protein-coding

Mus musculus

基因描述

Type Description
Definition pericentrin (kendrin)

研究结论

Date Results Publications
2019-11-30 11:44:00 CRISPR/Cas9-mediated knockout of Syne-2 in cell culture led to an overexpression and mislocalization of Pcnt and to ciliogenesis defects. This suggests that the Pcnt-Syne-2 complex is important for ciliogenesis and outer segment formation during retinal development and plays a role in nuclear migration. 30054381
2017-12-02 11:16:00 experiments demonstrate a role for Pericentrin in modulating Piezo2 activity and membrane expression in somatosensory neurons 27345391
2017-08-05 12:41:00 Meiotic division is highly error-prone in the absence of Pcnt and disrupted acentriolar microtubule-organizing centers. 28193732
2015-07-25 11:14:00 Pericentrin is a key functional component of the unique acentriolar MTOCs of mouse oocytes, and plays an important role in regulating meiotic spindle assembly and/or stability. 25266793
2015-06-20 11:06:00 The mouse Pcnt(-/-) phenotype was associated with misdirected ventricular septal growth in the heart, decreased proliferative symmetric divisions in brain neural progenitors, and increased misoriented divisions in fibroblasts. 25220058

名称对应

Type IDs
Synonymous AW476095, C86676, KEN, Pcnt2, kendrin, m239Asp, m275Asp
Gene
UniProtKB-ID: PCNT_MOUSE, Q80U10_MOUSE, F8VPV0_MOUSE, Q8CDL2_MOUSE, A0A1W2P737_MOUSE, Q3TQR8_MOUSE
UniprotKB: P48725, Q80U10, F8VPV0, Q8CDL2, A0A1W2P737, Q3TQR8
UniParc: UPI00003B0F26, UPI00000E9228, UPI0000E69BA7, UPI0000565249, UPI00005B1F66, UPI0000E69BA8, UPI0001CE9363, UPI0003ACF530
EMBL: AC141477, AK029906, AK122275, AC158618, AB207234, U05823, AB207233, AK163352
Ensembl: ENSMUSG00000001151
KO: mmu:18541
Nucleutide sequences
EMBL-CDS: BAF36560.1, BAF36559.1, AAA17886.1, BAC65557.2, BAC26669.1, BAE37314.1
Ensembl_TRS: ENSMUST00000001179, ENSMUST00000217838
Protein sequencees
Ensembl_PRO: ENSMUSP00000001179, ENSMUSP00000151534
RefSeq: XP_017169328.1, XP_036011579.1, XP_036011580.1, XP_017169330.1, XP_017169331.1, XP_017169334.1, XP_011241685.1, XP_036011581.1, XP_006513411.1, XP_006513419.1, XP_036011578.1, NP_032813.3, XP_017169327.1, XP_011241684.1, XP_006513416.1, XP_017169332.1, XP_030100810.1, XP_017169329.1, NP_001269921.1, XP_011241686.1, XP_036011577.1
Others
UniRef100: UniRef100_Q80U10, UniRef100_A0A1W2P737, UniRef100_P48725, UniRef100_Q8CDL2, UniRef100_F8VPV0, UniRef100_Q3TQR8
UniRef90: UniRef90_P48725, UniRef90_Q80U10
UniRef50: UniRef50_P48725
UniGene: Mm.251794
CCDS: CCDS88027.1

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