| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 8 |
| Date | Results | Publications |
|---|---|---|
| 2012-05-12 11:12:00 | The phosphorylation of the M3/6 phosphatase by JNK in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK activation. | 22100391 |
| 2010-01-21 00:00:00 | DUSP8 is genetically linked to alcohol dependence and was found on chromosome 11p15.5 | 13129832 |
| 2010-01-21 00:00:00 | Because this variant of hVH-5 lacked intronic sequences in its genomic structure, we suggest it might be a processed pseudogene of hVH-5. | 15899389 |
| Type | IDs |
|---|---|
| Synonymous | C11orf81, HB5, HVH-5, HVH8 |
| Gene |
UniProtKB-ID:
DUS8_HUMAN
UniprotKB:
Q13202
UniParc:
UPI000000DAD1
EMBL:
U27193,
AP006285,
BC045110,
BC038231
Ensembl:
ENSG00000184545,
ENSG00000273793,
ENSG00000278165
KO:
hsa:1850
|
| Nucleutide sequences |
EMBL-CDS:
AAA83151.1,
AAH45110.1,
AAH38231.1
Ensembl_TRS:
ENST00000610856,
ENST00000331588,
ENST00000625578,
ENST00000617829,
ENST00000397374,
ENST00000629053
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000479946,
ENSP00000481775,
ENSP00000487017,
ENSP00000380530,
ENSP00000329539,
ENSP00000487093
RefSeq:
NP_004411.2,
XP_011518235.1,
XP_011518234.1
|
| Others |
UniRef100:
UniRef100_Q13202
UniRef90:
UniRef90_Q13202
UniRef50:
UniRef50_O09112
UniGene:
Hs.41688
CCDS:
CCDS7724.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27880917 |
Cell Rep Nicole St-Denis , Gagan D Gupta , Zhen Yuan Lin , Beatriz Gonzalez-Badillo , Amanda O Veri , James D R Knight , Dushyandi Rajendran , Amber L Couzens , Ko W Currie , Johnny M Tkach , Sally W T Cheung , Laurence Pelletier , Anne-Claude Gingras |
2016-11-22 | - |
| 27432908 |
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Mol Cell Proteomics Xu Li , Kim My Tran , Kathryn E Aziz , Alexey V Sorokin , Junjie Chen , Wenqi Wang |
2016-09-01 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 23602568 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep Markku Varjosalo , Salla Keskitalo , Audrey Van Drogen , Helka Nurkkala , Anton Vichalkovski , Ruedi Aebersold , Matthias Gstaiger |
2013-04-25 |
MED6,
PDCD6IP,
FRAT1,
TROAP,
MED16,
RWDD2B,
HUWE1,
EDIL3,
ARPC1B,
HIPK3,
FRY,
AKAP9,
SUGP2,
RASA4,
CDK2,
RBM7,
CDK3,
CDK4,
PSME3,
CDK5,
FLOT1,
DDX39A,
CDK6,
CDK7,
HNRNPR,
DCAF7,
CDK8,
SRRM1,
CDK9,
SF3B4,
CDKN1A,
AKAP8,
CDKN1B,
STUB1,
CDKN1C,
CDKN2A,
PAK4,
CDKN2B,
ZNF267,
CDKN2C,
CDKN2D,
NPM2,
CACNG2,
RBM14,
HAX1,
BAIAP2,
PFDN6,
EIF3M,
SEC23B,
ENOX2,
MYBBP1A,
CHERP,
NOP56,
UBD,
MAB21L2,
DRAP1,
PRPF8,
CDC42EP3,
USP39,
PTGES3,
YME1L1,
NUP50,
HBS1L,
AHCYL1,
ZMYND11,
ZNF460,
CPSF4,
TRAFD1,
MAGED2,
RNPS1,
SUB1,
SRSF8,
AFG3L2,
MSL3,
STIP1,
EBNA1BP2,
SNRNP27,
STON1,
NUDT21,
CPSF6,
CHD2,
SNRNP35,
DIDO1,
WDR5,
KRR1,
FOXN3,
CLASRP,
KPTN,
WDR6,
SUPT16H,
CHEK2,
AKAP11,
EGLN2,
MED8,
GLCCI1,
GABARAP,
U2AF2,
CHUK,
EVI5L
|
| 22100391 |
Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite. Cell. Signal. Marina Cotsiki , Wolf Oehrl , Martina Samiotaki , Aspasia Theodosiou , George Panayotou |
2012-03-01 |
DUSP8,
MAPK8
|
| 21900206 |
A directed protein interaction network for investigating intracellular signal transduction. Sci Signal Arunachalam Vinayagam , Ulrich Stelzl , Raphaele Foulle , Stephanie Plassmann , Martina Zenkner , Jan Timm , Heike E Assmus , Miguel A Andrade-Navarro , Erich E Wanker |
2011-09-06 |
KCNE3,
HDAC6,
PDCD6IP,
ZNF605,
TOM1L1,
HMGXB4,
RANBP9,
RWDD2B,
SNUPN,
TSSC4,
ARPC3,
ACTR1B,
CDH13,
CEBPZ,
RBM5,
CDK4,
CDK5,
TRIM13,
EIF1,
DDX39A,
HNRNPR,
RABEPK,
SPRY2,
CDKN1A,
CDK2AP2,
LOC400927-CSNK1E,
RGS19,
CDKN2B,
DSCR3,
IKZF1,
NPM3,
TUBA1B,
TUBB3,
RACK1,
PIAS3,
NDC80,
YAP1,
CDIPT,
TUBGCP3,
TIMM17A,
TAB1,
FST,
STK25,
DEAF1,
KAT5,
GLRX3,
DCTN2,
PRDX4,
RABAC1,
DPYSL4,
CCT7,
CCT4,
DRAP1,
CENPB,
TXNIP,
NPRL2,
GNB5,
CERS1,
CFL1,
MGEA5,
PLK4,
RAI1,
GIPC1,
ZNF266,
UTP14A,
PGRMC1,
RAB10,
YIF1A,
JTB,
GADD45G,
AFG3L2,
C11orf58,
HNRNPA0,
PNRC1,
ADIRF,
COPS6,
IMMT,
SF3B2,
KIF2C,
RAB31,
ADAP1,
PIM2,
RCC1,
NUDT21,
SNRNP35,
CHD3,
STMN2,
HSF2BP,
SPACA9,
RPP14,
FGFR1OP,
FAF1,
ZWINT,
CHGA,
CDC37,
CHGB,
KAT7,
C14orf1,
NUDT5
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 17081983 |
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell Jesper V Olsen , Blagoy Blagoev , Florian Gnad , Boris Macek , Chanchal Kumar , Peter Mortensen , Matthias Mann |
2006-11-03 |
NR2E3,
ABI1,
TANK,
LINC00322,
CHAF1A,
TOM1,
DNAJB6,
SCAMP3,
HUWE1,
TSSC4,
COL4A3BP,
RAD50,
KIF20A,
PDIA6,
OPTN,
RBM12,
YAF2,
G3BP1,
ADGRG2,
CEBPZ,
PLXNC1,
TRIM28,
WASF2,
SORBS3,
RBM6,
RBM5,
CDK3,
TNK2,
MPHOSPH10,
MPHOSPH6,
TOPORS,
SRRM1,
STAM2,
ABCC4,
AKAP8,
STUB1,
UBE4B,
BET1,
SF3A1,
DNAJA2,
PAK4,
KATNB1,
ZNF267,
RTN3,
ADAR,
TRDN,
NPM3,
TUBB4B,
NDRG1,
BASP1,
YAP1,
CD2BP2,
PGRMC2,
SEC24B,
RBM14,
MCRS1,
CLGN,
LRRC41,
NCOA2,
SEMA4D,
SEMA4B,
MYBBP1A,
NOP56,
ANP32B,
RPP30,
ARFGEF2,
ARFGEF1,
CENPA,
DNPH1,
CENPC,
CDC42EP3,
PDLIM5,
TRIM3,
CENPE,
CENPF,
GAS2L1,
IGF2BP1,
KHDRBS3,
KHDRBS1,
CTCF,
CETN2,
USP39,
POLD3,
CFL1,
NUDC,
PTGES3,
CFL2,
STAG2,
RAI1,
KIF1C,
NUP50,
NES,
SRSF10,
WDR4,
SEPT9,
HSPH1,
UTP14A,
FAXDC2,
PPP1R13L
|
| 15899389 |
Identification of a transcriptionally active hVH-5 pseudogene on 10q22.2. Cancer Genet. Cytogenet. Ingemarie R Berger , Marcus Buschbeck , Johannes Bange , Axel Ullrich |
2005-06-01 |
DUSP8,
GLUD1P3
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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