| Type | Description |
|---|---|
| Definition | origin recognition complex, subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-11 12:01:00 | ORC1 in mice is essential for mitotic cell divisions but dispensable for endoreduplication. | 29967292 |
| 2010-01-21 00:00:00 | mouse Orc1, Orc2, and Orc3 each exist in two alternative-splicing variants and naturally occurring Orc1B lacks a functional domain that is essential for nuclear translocation and proteasome-dependent degradation | 15634681 |
| Type | IDs |
|---|---|
| Synonymous | AA545195, MmORC1, Orc1l |
| Gene |
UniProtKB-ID:
ORC1_MOUSE,
Q3UR71_MOUSE,
Q3TPY7_MOUSE
UniprotKB:
Q9Z1N2,
Q3UR71,
Q3TPY7
UniParc:
UPI0000022F2A,
UPI00005B200F,
UPI00005AC0B3
EMBL:
AK141741,
AL626783,
BC015073,
AJ003133,
AK164035
Ensembl:
ENSMUSG00000028587
KO:
mmu:18392
|
| Nucleutide sequences |
EMBL-CDS:
AAH15073.1,
CAA05890.1,
BAE24817.1,
BAE37598.1
Ensembl_TRS:
ENSMUST00000102744
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099805
RefSeq:
NP_035145.2
|
| Others |
UniRef100:
UniRef100_Q9Z1N2,
UniRef100_Q3UR71
UniRef90:
UniRef90_Q9Z1N2
UniRef50:
UniRef50_Q9Z1N2
UniGene:
Mm.294154
CCDS:
CCDS18453.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 29967292 |
Endoreduplication of the mouse genome in the absence of ORC1. Genes Dev. Takayuki Okano-Uchida , Lindsey N Kent , Madhu M Ouseph , Britney McCarty , Jeffrey J Frank , Raleigh Kladney , Maria C Cuitino , John C Thompson , Vincenzo Coppola , Maki Asano , Gustavo Leone |
2018-07-01 | - |
| 28700664 |
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One John P Sundberg , Soheil S Dadras , Kathleen A Silva , Victoria E Kennedy , Gaven Garland , Stephen A Murray , Beth A Sundberg , Paul N Schofield , C Herbert Pratt |
2017-01-01 | - |
| 27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
| 26584622 |
Genes Dev. Paulina A Latos , Arnold R Sienerth , Alexander Murray , Claire E Senner , Masanaga Muto , Masahito Ikawa , David Oxley , Sarah Burge , Brian J Cox , Myriam Hemberger |
2015-12-01 |
LOC100044627,
Rpl5,
LOC100862455,
Rpl31,
Ctnnd1,
Cct2,
Cct8,
Smc3,
Ddb1,
Dhx9,
Elf5,
Eomes,
Igf2bp1,
Wdr5,
Hspa5,
Hcfc1,
Hira,
Hspa9,
Ilf3,
Eif6,
Kpna2,
Matr3,
Mbd3,
Mki67,
Map1b,
Myef2,
Myo5a,
Ints6,
Orc1,
Pa2g4,
Pnn,
Rfc1,
Rpl10a,
Rpl19,
Rpl26,
Rpl27,
Rpl28,
Rpl30,
Rpl37a,
Rpl9,
Polr2a,
Rps15,
Sart1,
Scin,
Sin3a,
Snrpc,
Snrpb,
Bptf,
Zfp143,
Ints9,
Tfap2c,
Top1,
Top2b,
Tuba1c,
Ubp1,
Pphln1,
Yy1,
Zfp281,
Emsy,
Grhl2,
Esrrb,
Rpl23a,
Gtf3c4,
Rpl13,
Rpl7a,
Rpl3,
Gtse1,
Iqgap1,
Igf2bp2,
Chd7,
L1td1,
Hist1h1c,
Suz12,
Rplp1,
Prpf40a,
Rbm14,
Akap8,
Snd1,
Hic2,
Rpl23,
Rpl15,
Snrnp40,
Rbm25,
Rpl14,
Eif2s2,
Rpl4,
Hnrnpul2,
Flnc,
Vwa9,
Zcchc8,
Ints10,
Asun,
Skiv2l2,
Zmym2,
Zc3h18,
Rpl18a,
Ints7,
Ehmt1,
Zfp687
|
| 24457600 |
The central role of EED in the orchestration of polycomb group complexes. Nat Commun Qi Cao , Xiaoju Wang , Meng Zhao , Rendong Yang , Rohit Malik , Yuanyuan Qiao , Anton Poliakov , Anastasia K Yocum , Yong Li , Wei Chen , Xuhong Cao , Xia Jiang , Arun Dahiya , Clair Harris , Felix Y Feng , Sundeep Kalantry , Zhaohui S Qin , Saravana M Dhanasekaran , Arul M Chinnaiyan |
2014-01-01 | - |
| 22922362 |
Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat. Immunol. Dipayan Rudra , Paul deRoos , Ashutosh Chaudhry , Rachel E Niec , Aaron Arvey , Robert M Samstein , Christina Leslie , Scott A Shaffer , David R Goodlett , Alexander Y Rudensky |
2012-10-01 |
Ldlrap1,
Kifc1,
Noc4l,
Acacb,
Papd4,
Rrp8,
Clk3,
Csnk1d,
Tsr1,
Utp15,
Nckap1l,
Lpxn,
Whsc1,
Chd4,
Bre,
Camk2d,
Foxp1,
Nusap1,
Sp110,
Rap1a,
Sec13,
Rps6ka3,
Cse1l,
Pwp2,
Lims1,
Add1,
Adsl,
Akp3,
Ap1b1,
Ap2a1,
Ap3s1,
Arpc1b,
Atm,
Bax,
Bcl7c,
Bop1,
Runx1,
Cbfb,
Cbx4,
Cct4,
Cd2ap,
Cdk11b,
Cdk6,
Cebpz,
Coro1a,
Coil,
Dbnl,
Dbt,
Dync1h1,
Dnm2,
Ddx19a,
Elf1,
Mark2,
Ercc3,
Igf2bp3,
Fasn,
Fen1,
Gata3,
Nr3c1,
Gspt1,
H1f0,
Hdac2,
Hdac3,
H2afx,
Hk2,
Hnrnpl,
Inpp5d,
Kif11,
Kif4,
Kpna3,
Lat,
Arhgef1,
Lig3,
Nup155,
Pfkfb3,
Max,
Mllt10,
Msh6,
Map4,
Myef2,
Nfatc2,
Ints6,
Zfp638,
Npm3,
Orc1,
Orc2,
Pcx,
Pdcd4,
Pdcd6ip,
Pfkl,
Plec,
Plk1,
Lcp1,
Pold1,
Nup88,
Prpf4b,
Psme3,
Slu7,
Qk
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21565611 |
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell Liyun Sang , Julie J Miller , Kevin C Corbit , Rachel H Giles , Matthew J Brauer , Edgar A Otto , Lisa M Baye , Xiaohui Wen , Suzie J Scales , Mandy Kwong , Erik G Huntzicker , Mindan K Sfakianos , Wendy Sandoval , J Fernando Bazan , Priya Kulkarni , Francesc R Garcia-Gonzalo , Allen D Seol , John F O'Toole , Susanne Held , Heiko M Reutter , William S Lane , Muhammad Arshad Rafiq , Abdul Noor , Muhammad Ansar , Akella Radha Rama Devi , Val C Sheffield , Diane C Slusarski , John B Vincent , Daniel A Doherty , Friedhelm Hildebrandt , Jeremy F Reiter , Peter K Jackson |
2011-05-13 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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