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181727 aak-2

181727

aak-2

5'-AMP-activated protein kinase catalytic subunit alpha-2

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition 5'-AMP-activated protein kinase catalytic subunit alpha-2

研究结论

Date Results Publications
2020-08-22 15:30:00 relationships between metabolism and DAF-16 subcellular localization in Caenorhabditis elegans revealed by a novel fluorometric method. 31152844
2019-04-13 10:14:00 AMPK functions downstream of, or in parallel with DAF-18/PTEN and insulin/IGF-1 signaling to inhibit PP2A function. 30487179
2018-06-02 10:25:00 mir-259 functioned in pharynx-intestinal valve and RSKS-1 functioned in pharynx to regulate MWCNTs toxicity. Furthermore, RSKS-1 regulated MWCNTs toxicity by suppressing the function of AAK-2-DAF-16 signaling cascade. Our results will strengthen our understanding the microRNAs mediated protection mechanisms for animals against the toxicity from certain nanomaterials. 27573184
2017-12-02 12:25:00 Transcription factors CEP-1 and CEH-23 collaborate with AAK-2 to modulate longevity in Caenorhabditis elegans. 28560849
2017-05-27 10:16:00 he results revealed that inactivation of several genes restores gonad elongation, including aak-2, which encodes the catalytic subunit of AMP-activated protein kinase (AMPK). We then generated triple mutant worms for cnnm-1; cnnm-3; aak-2 and confirmed that the aak-2 mutation also suppressed the defective gonadal elongation in cnnm-1; cnnm-3 mutant worms. 27564576

名称对应

Type IDs
Gene
UniProtKB-ID: AAPK2_CAEEL
UniprotKB: Q95ZQ4
UniParc: UPI000007C20F, UPI0000082CDB, UPI00001755D7
EMBL: FO081053, AY347273
EnsemblGenome: WBGene00020142
KO: cel:CELE_T01C8.1
Nucleutide sequences
EMBL-CDS: CCD68835.1, CCD68833.1, AAR06928.1, CCD68834.1
Gene_ORFName: T01C8.1
EnsemblGenome_TRS: T01C8.1c.2, T01C8.1b.1, T01C8.1c.1, T01C8.1a.1
Protein sequencees
EnsemblGenome_PRO: T01C8.1c.2, T01C8.1c.1, T01C8.1b.1, T01C8.1a.1
RefSeq: NP_510710.2, NP_001024868.1, NP_510711.2
Others
UniRef100: UniRef100_Q95ZQ4
UniRef90: UniRef90_Q95ZQ4
UniRef50: UniRef50_Q95ZQ4
UniGene: Cel.17479

全选

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