| Type | Description |
|---|---|
| Definition | Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-24 10:42:00 | Suggest mbk-1 as a novel regulator of C. elegans longevity upon both, germline ablation and DAF-2 inhibition, and provide evidence for mbk-1 regulating DAF-16 activity in germline-deficient animals. | 28562327 |
| 2010-12-04 10:23:00 | These data support a model in which SWAN-1, MBK-1 and EGL-9 regulate HIF-1 transcriptional activity and modulate C. elegans resistance to P. aeruginosa PAO1 fast killing. | 20865124 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MBK1_CAEEL
UniprotKB:
Q8WQL7
UniParc:
UPI000000CA75
EMBL:
AY064464,
Z69885
EnsemblGenome:
WBGene00003149
KO:
cel:CELE_T04C10.1
|
| Nucleutide sequences |
EMBL-CDS:
CAA93756.2,
AAL40874.1
Gene_ORFName:
T04C10.1
EnsemblGenome_TRS:
T04C10.1.1
|
| Protein sequencees |
EnsemblGenome_PRO:
T04C10.1.1
RefSeq:
NP_510460.2
|
| Others |
UniRef100:
UniRef100_Q8WQL7
UniRef90:
UniRef90_Q8WQL7
UniRef50:
UniRef50_Q8WQL7
UniGene:
Cel.22462
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28562327 |
Aging (Albany NY) Hildegard I D Mack , Peichuan Zhang , Bryan R Fonslow , John R Yates |
2017-05-25 | - |
| 26912668 |
Mol Cell Proteomics Jia-Xuan Chen , Patricia G Cipriani , Desirea Mecenas , Jolanta Polanowska , Fabio Piano , Kristin C Gunsalus , Matthias Selbach |
2016-05-01 | - |
| 23549480 |
SH3 interactome conserves general function over specific form. Mol Syst Biol Xiaofeng Xin , David Gfeller , Jackie Cheng , Raffi Tonikian , Lin Sun , Ailan Guo , Lianet Lopez , Alevtina Pavlenco , Adenrele Akintobi , Yingnan Zhang , Jean-François Rual , Bridget Currell , Somasekar Seshagiri , Tong Hao , Xinping Yang , Yun A Shen , Kourosh Salehi-Ashtiani , Jingjing Li , Aaron T Cheng , Dryden Bouamalay , Adrien Lugari , David E Hill , Mark L Grimes , David G Drubin , Barth D Grant , Marc Vidal , Charles Boone , Sachdev S Sidhu , Gary D Bader |
2013-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20865124 |
PLoS Pathog. Zhiyong Shao , Yi Zhang , Qi Ye , Jenifer Neeta Saldanha , Jo Anne Powell-Coffman |
2010-01-01 |
egl-9,
swan-1,
hif-1,
mbk-1
|
| 19447967 |
Shifted Transversal Design smart-pooling for high coverage interactome mapping. Genome Res. Xiaofeng Xin , Jean-François Rual , Tomoko Hirozane-Kishikawa , David E Hill , Marc Vidal , Charles Boone , Nicolas Thierry-Mieg |
2009-07-01 |
lin-65,
F23C8.8,
sop-3,
unc-11,
ceh-17,
M04F3.5,
C06A5.8,
lin-10,
C17E4.10,
rsy-1,
abu-11,
T02H6.5,
ZK1240.1,
ubc-15,
dhs-5,
ifb-1,
ehs-1,
fkh-8,
szy-4,
toe-2,
mig-5,
K10H10.4,
Y55B1BR.2,
pat-12,
F23H11.4,
exc-6,
F34D10.4,
abi-1,
mdt-15,
T04C9.1,
C05D10.4,
lim-8,
cyk-1,
F08F8.9,
mig-10,
nhl-1,
rde-4,
athp-1,
T12D8.9,
Y41D4A.5,
snn-1,
M57.1,
C06G3.6,
deb-1,
C49H3.6,
wsp-1,
mpst-5,
T11B7.1,
alp-1,
rad-51,
gei-18,
eps-8,
Y50D4A.4,
nhr-114,
figl-1,
B0507.3,
unc-23,
egl-9,
secs-1,
sas-5,
rnp-1,
ttx-1,
swsn-1,
sli-1,
zfp-3,
F41B4.1,
C11E4.6,
rrc-1,
vab-3,
abl-1,
hpo-34,
mbk-1,
F45B8.3,
dyn-1,
C09G1.4,
F09C8.2,
F52E10.4,
C06G1.5,
tag-343,
ztf-2,
F32B4.4,
F42G2.5,
hum-10,
srt-36,
K04F10.2,
wve-1,
R11F4.3,
mab-10,
ddl-2,
magu-1,
grd-7,
klp-3,
pcf-11,
sorb-1,
sap-49,
COL4A3BP,
RBM7,
CDK4,
CDKN2B
|
| 15990870 |
EMBO J. Alexander Gottschalk , Ruta B Almedom , Thorsten Schedletzky , Scott D Anderson , John R Yates , William R Schafer |
2005-07-20 |
W02H5.16,
hsp-2,
chaf-2,
sep-1,
unc-89,
met-1,
pat-10,
rpt-5,
unc-87,
cyc-1,
D1081.7,
unc-29,
snpc-4,
nra-2,
tba-1,
tba-2,
aex-5,
B0432.13,
fbxb-41,
cdc-48.1,
tba-4,
F44E5.1,
patr-1,
tufm-1,
tbb-2,
rps-1,
ins-17,
rps-0,
tag-174,
mlc-3,
wrm-1,
ubq-1,
T20B12.3,
fbn-1,
best-24,
tlk-1,
umps-1,
sca-1,
T05D4.3,
act-5,
mca-2,
ribo-1,
rps-8,
cav-1,
F13B12.1,
tax-6,
F01G4.6,
ccr-4,
hsp-1,
nra-1,
F33E11.3,
cmd-1,
hsp-6,
act-3,
act-2,
act-1,
T04F3.1,
K01D12.15,
K01D12.7,
ril-1,
tni-3,
mlt-11,
act-4,
acn-1,
inx-3,
hsp-3,
mup-2,
tnt-2,
mbk-1,
kin-20,
let-2,
C36E6.2,
mlc-2,
srv-17,
str-245,
mltn-3,
mltn-4,
cal-6,
srh-291,
ssl-1,
B0432.9,
Y48G1C.8,
cdgs-1,
Y71G12B.30,
let-526,
mltn-5
|
| 14704431 |
A map of the interactome network of the metazoan C. elegans. Science Siming Li , Christopher M Armstrong , Nicolas Bertin , Hui Ge , Stuart Milstein , Mike Boxem , Pierre-Olivier Vidalain , Jing-Dong J Han , Alban Chesneau , Tong Hao , Debra S Goldberg , Ning Li , Monica Martinez , Jean-François Rual , Philippe Lamesch , Lai Xu , Muneesh Tewari , Sharyl L Wong , Lan V Zhang , Gabriel F Berriz , Laurent Jacotot , Philippe Vaglio , Jérôme Reboul , Tomoko Hirozane-Kishikawa , Qianru Li , Harrison W Gabel , Ahmed Elewa , Bridget Baumgartner , Debra J Rose , Haiyuan Yu , Stephanie Bosak , Reynaldo Sequerra , Andrew Fraser , Susan E Mango , William M Saxton , Susan Strome , Sander Van Den Heuvel , Fabio Piano , Jean Vandenhaute , Claude Sardet , Mark Gerstein , Lynn Doucette-Stamm , Kristin C Gunsalus , J Wade Harper , Michael E Cusick , Frederick P Roth , David E Hill , Marc Vidal |
2004-01-23 | - |
| 9851916 |
Genome sequence of the nematode C. elegans: a platform for investigating biology. Science C. elegans Sequencing Consortium |
1998-12-11 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员