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180873 pak-1

180873

pak-1

Serine/threonine-protein kinase pak-1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Serine/threonine-protein kinase pak-1

研究结论

Date Results Publications
2014-06-14 13:51:00 FOXO-Pak1 pathway was recently shown to regulate mammalian neuronal polarity, our findings indicate that the roles of FOXO and Pak1 in neuronal migration are most likely conserved from C. elegans to higher organisms. 23994474
2013-08-10 10:36:00 PAK1 promotes reproduction, whereas it inactivates HSP16.2 gene and shortens lifespan. 23524941
2012-12-08 10:25:00 Pak-1 interacts with Wnt signaling to regulate tissue polarity and gene expression. 23019370
2010-01-21 00:00:00 Data show that combined loss of ROCK and PAK, or ROCK and MRCK, completely prevented embryonic elongation, but a constitutively active form of MLC-4 could only rescue a lack of MRCK. 19675126
2010-01-21 00:00:00 only PAK-1 functions in the GIT/PIX/PAK pathway independently of RAC/CDC42 GTPases. 19023419

名称对应

Type IDs
Gene
UniProtKB-ID: PK1_CAEEL
UniprotKB: Q17850
UniParc: UPI0000418DB7, UPI000000C9BA, UPI0000060ED8, UPI0000060ED9
EMBL: D83215, FO080450, U63744
EnsemblGenome: WBGene00003911
KO: cel:CELE_C09B8.7
Nucleutide sequences
EMBL-CDS: CCD63804.1, CCD63806.1, BAA11844.1, CCD63807.1, AAC47308.1, CCD63805.1
Gene_ORFName: C09B8.7
EnsemblGenome_TRS: C09B8.7e.1, C09B8.7b.1, C09B8.7a.1, C09B8.7c.1
Protein sequencees
EnsemblGenome_PRO: C09B8.7c.1, C09B8.7a.1, C09B8.7b.1, C09B8.7e.1
RefSeq: NP_001024379.1, NP_001024377.1, NP_001024378.1
Others
UniRef100: UniRef100_Q17850
UniRef90: UniRef90_Q17850
UniRef50: UniRef50_Q13153
UniGene: Cel.17920

全选

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研究热度

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